Inflammation 1 Flashcards
What vascular changes occur in response to injury?
vasodilation, rubor and calor
What is white cell margination?
when vasodilation occurs the rate of flow slows this allows white blood cells to move peripherally
What does VCAM and ICAM stand for?
vascular cellular adhesion molecule and intracellular adhesion molecule
Histamine and Thrombin from inflammatory cells increase what?
selection expression
What 2 molecules increase endothelial cell expression of ICAM and VCAM?
IL-1 and TNF
vessels become what in response to injury?
leaky
What follows proteins?
water so swelling occurs
What is chemotaxis?
cells follow a chemical gradient and so move along it
How does bacteria stand out from crowd?
coated in proteins
What happens in englulfment?
vesicle forms and joins with lysosome to form phagolysosome
What is vital for degradation and killing?
reactive nitrogen and oxygen species
What is dolor?
pain
