Med ed revision session: pharmacology

Question 1

Potency

Answer 1

(ec 50) most potent requires least amount of drug

Question 2

Efficacy

Answer 2

always the highest (max effect the drug can elicit)

Question 3

Competitive antagonist

Answer 3

same shape curve displaced to right

Question 4

Non comp antagonist

Answer 4

drug never reaches max efficacy

Question 5

Therapeutic index

Answer 5

td50 divided by ed 50

Question 6

first pass metabolism

Answer 6

goes through gi tract before bloodstream. this is why oral does higher than iv dose

Question 7

when need to adjust dose?

Answer 7

if have liver failure, low meatabolism more drug in blood stream

Question 8

% infusion

Answer 8

grams per 100 mils

Question 9

g protein

Answer 9

g protein moves activates another protein

Question 10

steroid hormones

Answer 10

have intracellular effect, can go straight to transcription factors

Question 11

pharmokinetics

Answer 11

Pharmacokinetics is the study of the way in which drugs move through the body

Question 12

pharmodynamics

Answer 12

The effect that drugs have on the body