Medications Flashcards

1
Q

Antipsychotics:

Name 4 atypical (New) antipsychotic medications?

Hint (New - 2A C O Q R Z)

A
  • Amisulpride
  • Aripiprazole
  • Clozapine
  • Olanzapine
  • Quetiapine
  • Risperidone
  • Ziprasidone
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2
Q

Antipsychotics:

Name 2 typical (conventional, 1st generation, old) antipsychotic medications?

Hint (Old - C D F H P T T Z)

A
  • Chlorpromazine
  • Droperidol
  • Fluphenazine,
  • Haloperidol
  • Pericyazone
  • Thioridazine
  • Trifluoperazine
  • Zuclopenthixol acetate
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3
Q

Antipsychotics:

What conditions are antipsychotic medications aimed at treating?

A
  • Schizophrenia
  • Acute mania
  • Psychotic depression
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4
Q

What are extrapyramidal side effects?

A
  • Dystonia
  • Akathisia
  • Parkinsonism
  • Bradykinesia
  • Tardive dyskinesia
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5
Q

What is dystonia?

A

Continuous spasms and muscle contractions

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6
Q

What is akathisia?

A

Motor restlessness

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7
Q

What is parkinsonism?

A

Characteristic symptoms such as rigidity, bradykinesia (slowness of movement), and tremor

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8
Q

What is tardive dyskinesia

A

Irregular, jerky movements - generally tongue, lips and feet

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9
Q

What antipsychotic medications are contraindicated in patients with Parkinson’s disease?

A
  • Prochlorperizine
  • Chlorpromazine
  • Pimozide
  • Halperidol
  • Droperidol
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10
Q

What atypical antipsychotic is contraindicated in patients with severe cardiac disease?

A

Clozapine

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11
Q

What is neuroleptic malignant syndrome (NMS)?

A

A side effect from antipsychotics

S and S:

  • High fever
  • Muscular rigidity
  • Altered mental state/delirium
  • Autonomic instability
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12
Q

What is a common side effect of antipsychotic medication which can lead to further problems?

A

Weight gain/Obesity

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13
Q

What is the one extrapyramidal side effect which is irreversible if not detected when a person is on antipsychotic medications?

A

Tardive dyskinesia (irregular jerky movement)

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14
Q

What is the therapeutic dose for Clozapine?

A

Slow start up to 300-450mg per day in divided doses

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15
Q

What is the maximum recommended dose of Clozapine?

A

900mg daily

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16
Q

What is the therapeutic dose for Halperidol?

A

0.5-5mg daily

Severe symptoms 5 - 15mg daily

17
Q

What is the therapeutic dose for Olanzapine when treating schizophrenia?

A

5-10mg daily

18
Q

What is the therapeutic dose for Olanzapine when treating Acute mania?

A

10-15mg on its own
OR
10mg if given with lithium or valporate

19
Q

What is Relprev?

A

A depot injection of olanzapine

20
Q

What is the purpose of medication with anticholinergic properties?

A

Used to treat the side effects of anti-psychotic drugs, such as restlessness, dry mouth, tremor

21
Q

What are two examples of anti cholinergic medication?

hint (B P)

A
  • Benzetrophrine.

- Procycladine

22
Q

What is occulargyrocrisis?

A

Adverse effect to antipsychotic medication.

  • Rigidity
  • Neck flexes back
  • Eyes roll upward
  • No control over reaction
23
Q

How do antidepressants work?

A

Block the reuptake of neurotransmitters (serotonin and noradrenaline)

Allows more serotonin and noradrenaline to transmitted

24
Q

How do antipsychotic medications work?

A

Block dopamine receptors

Allow more dopamine to be transmitted

25
Q

Benzodiazepines facilitate the transmission of …………..what?

A

Gamma-aminobutyric acide (GABA).

26
Q

Amphetamines increase ………………., ………………….. and ……………………..?

A
  • norepinephrine
  • serotonin
  • dopamine
27
Q

What is the time limit on anxiolytic medications?

A

Use no longer than 4 months

28
Q

What can anxiolytics be used to treat in addition to anxiety?

Hint (3)

A
Alcohol withdrawal
AND
Skeletal muscle spasms
AND
Preoperative sedation
29
Q

What populations should you take precautions with when using anxiolytics?

A
  • Older

- Children

30
Q

What other medications/substances may interact with anxiolytics which mean extreme caution should be used?

A
  • Alcohol and other CNS depressants
31
Q

What are the therapeutic serum levels for lithium carbonate?

A

0.6 - 1.2

32
Q

What are possible side effects of Lithium Carbonate?

A
  • Toxicity – potentially fatal
  • Nausea
  • Tremor
  • Polydipsia
  • Polyuria
  • Lack of emotional range
33
Q

What is Lithium Carbonate primarily indicated for?

A
  • Bipolar
  • Mania
  • To augment other medications
34
Q

How does anti Parkinson medications work??

A
  • Restores natural balance of acetylcholine & dopamine in CNS
35
Q

What are two common anti Parkinson medications?

A
  • Benztropine

- Procyclidine

36
Q

What is one very detrimental side effect of Clozapine to encourage special caution with its use?

A

Agranulocytosis.

Reduce white blood cell count, flu like symptoms

37
Q

What is one very detrimental side effect of Zuclopenthixol that should encourage special caution with its use?

A
  • Rapid sedation antipsychotic
  • Hyper sedation
  • Hypotension
  • Respiratory distress/depressant
  • Currently on the decline in practice
38
Q

What is another name for Zuclopenthixol?

A

Accuphase