Hog Cholera and ASF Flashcards

1
Q

What is another name for Hog cholera?

A

Classical swine fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What family is Hog cholera in?

A

Flaviviridae (same as BVD in cattle)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Is Flaviviridae an enveloped or naked virus?

A

Enveloped

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the mortality and morbidity for Hog cholera?

A

High morbidity AND high mortality

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Is Hog Cholera in the US?

A

Hog cholera is eradicated in the US

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the clinical signs of Hog Cholera?

A

High fever, depression, anorexia, conjunctivitis
Vomiting/diarrhea/constipation
Paraesis, paralysis, circling tremors, convulsions
Leukopenia
Hyperemia and purpura of abdomen and ears

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

You arrive at a farm and see several pigs displaying neuro signs from paralysis, to circling tremors and convulsions. When you get closer you notice hyperemia and purpura of abdomen and ears. What disease do these pig have?

A

Hog cholera in the flaviviridae family

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Would a pig with hog cholera have respiratory issues?

A

A pig with hog cholera could have 2ry bacterial pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

T/F, young swine are less susceptible to Hog cholera?

A

False, young swine (and all naive animals) die very quickly without clinical signs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How long can a pig with hog cholera survive?

A

One or two weeks, they may die from 2ry bacterial infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How does hog cholera affect a pregnant sow?

A

Abortion, resorption, fetal mummification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How does hog cholera affect a newborn?

A

Tremors, runts, death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Could a pig have subacute or chronic hog cholera?

A

Yes, if they live in an endemic area. Strains of moderate virulence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the common entry point of hog cholera?

A

Ingestion, with 1ry replication in the tonsils.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where is the 2ry replication in hog cholera?

A

Endothelial cells, lymphoid organs, bone marrow, hemorrhages, leukopenia and thrombocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

You suspect hog cholera, but upon necropsy you see no lesions. Why?

A

Peracute case, no time for lesions to evolve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

You perform a necropsy on a pig, and see infraction of the spleen. What two diseases do you suspect?

A

African swine fever and hog cholera

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

You perform a necropsy on a pig and see the following: petechial hemorrhages, congestion, infarction of the spleen, liver, bone marrow and lungs. You also see DIC. What disease and family?

A

Hog cholera, flaviviridae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is commonly seen in subacute or chronic cases of hog cholera?

A

Necrotic ulceration of the mucosa of the large intestines, and opportunistic 2ry bacterial pneumonia and enteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the MOST PROMINENT lesion seen at necropsy in a pig with hog cholera?

A

General exhaustion of the lymphoid system (atrophy of thymus, spleen and LNs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

If a sow with hog cholera gives birth, and the some of the piglets survive, others do not. Why? Should you be concerned with the healthy ones?

A

Placental attachment, only some get infected. The healthy ones are still life-long shedders!

22
Q

How do you diagnose hog cholera?

A

IF in tissues and antigen ELISA (best)
Virus Isolation and neutralization
Must be sent to an authorized lab!

23
Q

Is hog cholera notifiable?

A

In most countries

24
Q

Can you use serology in hog cholera?

A

Yes, but not for outbreaks or for testing an incoming animal (PI will not seroconvert)
Epidemiology/circulating strains

25
Q

How is hog cholera transmitted?

A

Direct or indirect (fomites!)

PI (or in-apparently infected swine)

26
Q

What is the best control method for hog cholera?

A

Test and slaugther

27
Q

How could you explain an outbreak of hog cholera in a clean herd?

A

Bringing in a PI or in-apparently infected swine

Garbage-feeding was a common source

28
Q

Your farm has a outbreak of hog cholera, is it okay to cull the pigs and freeze the meat so the virus dies, making it safe for consumption?

A

No, hog cholera virus survives for a long time in freezing temperatures

29
Q

Are there vaccines for hog cholera?

A

Yes, attenuated vaccines

30
Q

What virus family causes African Swine Fever?

A

Asfaviridae

ASF = ASFaviridae

31
Q

Is Asfaviridae a DNA or RNA virus?

A

DNA, enveloped

32
Q

What virus/disease causes paracrystalline arrays in the cytoplasm of cells?

A

Asfaviridae

African Swine Fever

33
Q

T/F, the envelop of Asfaviridae (African swine fever) makes it more virulent?

A

False, the envelope is NOT necessary for virus infectivity

34
Q

Is African Swine Fever zoonotic?

A

No

35
Q

What are the reservoirs and vectors of African Swine Fever?

A

Warthogs (asymptomatic) and soft ticks

36
Q

In African Swine Fever, who has a higher viremia, young or old warthogs?

A

Young warthogs have a higher virema

37
Q

What is the mortality of African Swine Fever?

A

100%

38
Q

What are the clinical signs of African Swine Fever?

A

High fever, diarrhea, incoordination, postration.
Dyspnea, vomiting, nasal and conjunctival discharge, reddening or cyanosis of ears and snout, hemorrhages from nose and anus

39
Q

What happens to a pregnant sow infected with ASF?

A

She aborts

40
Q

How is ASF transmitted?

A

Infected meat and ticks

41
Q

You are waiting on test results to see if pigs you saw recently has ASF or hog cholera. Which one would be more of a concern if you didn’t infect your boots when going to the next farm?

A

Hog cholera – can be transmitted by fomites

ASF – can be transmitted by infected meat or ticks

42
Q

You are waiting on test results to see if pigs you saw recently has ASF or hog cholera. Which one would be more of a concern if you didn’t infect your boots when going to the next farm?

A

Hog cholera – can be transmitted by fomites

ASF – can be transmitted by infected meat, PI pigs or ticks

43
Q

What is chronic disease of ASF characterized by?

A

Cutaneous ulcers, pneumonia, pericarditis, pleuritis and arthritis

44
Q

What is chronic disease of ASF characterized by?

A

Cutaneous ulcers, pneumonia, pericarditis, pleuritis and arthritis

45
Q

What diagnostic test is best for ASF?

A

Detection of viral antigen (IF and Ag ELISA)

46
Q

Can you do virus isolation in ASF?

A

Yes, but it is not a good idea. You need a fast test so you can get results and quarantine infected ones

47
Q

Is there a vaccine for ASF?

A

No

48
Q

What is the best control for ASF?

A

Strict import rules (no import from ASF countries), destruction of waste food scraps from ships/planes in foreign areas & testing

49
Q

How can you break the sylvatic cycle in African Swine Fever?

A

You cannot (you would have to remove all ticks from wild hogs)

50
Q

Why are there no vaccines for ASF?

A

Receptors of the virus are not on the envelope, the receptors are protected by the envelope (hidden)
Pigs do not respond well enough to the vaccine to have immunity