Rheumatology Flashcards

1
Q

Rheumatoid arthritis

A

RF

ACCP (ACPA) anti-cyclic citrullinated peptide antibodies

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2
Q

HLA B27

A

seronegative arthropathies –> ank spons, reactive arthritis, psoriatic arthritis, enteropathy (ICBD)
juvenile arthritis, anterior uveitis

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3
Q

ANA

A
CTDs -->
SLE (80-90%)
systemic sclerosis (80%)
polymyositis/dermatomyositis (30%)
also seen in autoimmune chronic active hepatitis, PBC, IE, fibrosing alveolitis
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4
Q

SLE

A

ANA 99% +ve
anti-dsDNA
anti-smith

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5
Q

HLA DR4

A

RA

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6
Q

ANCA

A

systemic vasculitis

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7
Q

limited systemic sclerosis (scleroderma)

A

anti-centromere antibodies

ANA

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8
Q

diffuse systemic sclerosis (scleroderma)

A

scl70, topoisomerase

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9
Q

rheumatoid factor

A

rheumatoid arthritis

sjogren’;s syndrome

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10
Q

Sjogren’s

A

RF in 100%
ANA in 70%
Anti-Ro and La

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11
Q

polymyositis/dermatomyositis

A

ANA

anti-Jo

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12
Q

antiphospholipid syndrome

A

anticardiolipin antibody

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