Lipids Flashcards
1
Q
Adsorbs cholesterol, lowers LDL
A
Fiber
2
Q
increases TGs clearance, decreases VLDL
A
Omega 3 Fatty Acids
3
Q
Statin (lipophilic)
A
Atorvastatin (CYP3A4) (admin anytime)
4
Q
Statin (hydrophilic)
A
Pravastatin (sulfation, not P450) (admin at night) (urine unchanged)
5
Q
Absorption blocker
A
Ezetimibe (not P450)(active metabolites)
6
Q
bile acid sequestrant/resin
A
Cholestyramine (adjunct with statins)(might raise TGs)(upregs reductase)
7
Q
Increases HDL
A
Niacin (Vitamin B3)(decreases LDL/TGs)
8
Q
decreases TGs
A
Gemfibrozil (inhibits CYPs) (CI:renal/hepatic dysfunction)
9
Q
PCSK9 inhibitor
A
Evolocumab
