Depression Flashcards

1
Q

F:M depression

A

2:1

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2
Q

Screening questions for depression

A
  • Over last mo, have you been bothered by feeling down, depressed or hopeless?
  • over the last mo, have you been bothered by having little interest or pleasure in doing things?
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3
Q

Core sx of depression

A
  • persistent low mood
  • loss of interest/pleasure
  • fatigue
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4
Q

Other sx of depression

A
disturbed sleep
poor concentration
low self esteem
change in appetite
suicidal thoughts
feeling of worthlessness/guilt
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5
Q

DSM IV use

A

assesses number of core and general sx of depression present

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6
Q

What is sub threshold depression

A

4 or fewer of DSM IV depression sx is sub threshold depression

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7
Q

What is Dysthymia

A

Sub threshold depression persisting for 2 yrs

aka chronic subthreshold depression

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8
Q

What is the questionnaire for depression

A

PHQ-9

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9
Q

Stepped care model of depression mx

A

Step 1: known or suspected presentations of depression
Step 2: persistent sub threshold or mild to moderate depression
Step 3: persistent sub threshold or mild to moderate depression with inadequate response to step 2 and Moderate to severe depression
Step 4: Severe and complex depression; severe self-neglect

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10
Q

Step 1 mx of depression

A

Support,
Psychoeducation
Active monitoring

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11
Q

Step 2

A

low intensity psychological interventions (eg Cognitive behavioural therapy, CBT or structured group physical activity programme)
Consider meds/referral if sx persist

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12
Q

Step 3

A
  • Meds

- high intensity psychological interventions (one to one psychotherapy)

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13
Q

Step 4

A
  • meds
  • high intensity psychological interventions (one to one psychotherapy)
  • electroconvulsive therapy
  • crisis services
  • in patient care
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14
Q

Problem solving therapy

A

step 2 mx

  • write a list of problems,
  • rank them in order of importance
  • suggest solutions
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15
Q

Cognitive behavioural therapy (CBT)

A
  • changing the way pt think/react
  • may involve systemic desensitisation (behavioural method)
  • or focussing on peoples thoughts and reasoning to challenge assumptions
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16
Q

Mindfullness based cognitive therapy

A

for people who are well currently but have a hx of 3 prvs depressions

17
Q

How long do most antidepressants take to work

A

1-2 wks

18
Q

How long for antidepressants to reach their peak effect

A

4-6 wks

19
Q

When most SEs of antidepressants start to ease

A

2 wks post start

20
Q

Main SEs of most antidepressants

A

GI problems:
- nause
- dry mouth
Increased anxiety

21
Q

Monitoring after starting on antidepressants

A

Every 2 peaks until stable

Unless <30 or increased risk of suicide (every 1 wk)

22
Q

How long should a course of antidepressants be

A

6 mo, but can be longer if they opt for it

- if 2 or more episodes of major depression, then 2 yrs

23
Q

Discontinuation reaction to antidepressants

A
  • if used more than 2mo, then suddenly stopped

- sx include headache, nausea, paraesthesia, dizziness, anxiety

24
Q

How to avoid discontinuation reaction to antidepressants

A

weaning off over a period of about 1 mo

25
Q

Meds used for depressin

A
SSRI
SNRI
TCA
MAOi
Mirtazapine
26
Q

SSRI examples

A

citalopram,
fluoxetine,
paroxetine
sertraline (fewest interactions)

27
Q

SNRI examples

A

Duloxetine or venlafaxine

28
Q

TCA example

A

Lofepramine

29
Q

MAOi example

A

phenelzine

30
Q

Mirtazapine mech of action

A

presynaptic alpha2 antagonist