Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

RITE COPY > Behavioral Neurology > Flashcards

Behavioral Neurology Flashcards

1
Q

hyperintensity of the caudate and putamen; cortical ribbon on MRI

A

CJD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q
  • rapidly progressive mental deterioration
  • myoclonus (provoked by startle)
  • extrapyramidal signs (hypokinesia, rigidity)
  • cerebellar manifestations (nystagmus, ataxia)
  • visual disturbance
  • akinetic mutism
A

CJD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

positive 14-3-3 protein in CSF

A

CJD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pathology: loss of neurons, spongiform degeneration, or plaques positive for PrPSc

A

CJD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Clinical features of CJD

A
  • rapidly progressive mental deterioration
  • myoclonus (provoked by startle)
  • extrapyramidal signs (hypokinesia, rigidity)
  • cerebellar manifestations (nystagmus, ataxia)
  • visual disturbance
  • akinetic mutism
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What clinical symptoms are most compatible with the disease process seen in the picture?

a) Dementia, social disinhibition
b) Memory loss, language deficits, visuospatial impairment
c) Acute course of hypersalivation, hydrophobia, encephalopathy & death
d) Writhing fluid movements, ataxia, psychosis
e) Parkinsonism, hallucinations, neuroleptic sensitivity

A

Lewy Body Dementia

e) Parkinsonism, hallucinations, neuroleptic sensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What clinical symptoms are most compatible with the disease process seen in the picture?

a) Dementia, social disinhibition
b) Memory loss, language deficits, visuospatial impairment
c) Acute course of hypersalivation, hydrophobia, encephalopathy & death
d) Writhing fluid movements, ataxia, psychosis
e) Parkinsonism, hallucinations, neuroleptic sensitivity

A

Alzheimer’s Disease

b) Memory loss, language deficits, visuospatial impairment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are 5 things that can be seen on pathology in Alzheimer’s Disease?

A

Neuritic Plaques

Neurofibrillary Tangles

Hirano Bodies

Neuronal Granulovacuolar degeneration

Deposition of Amyloid in blood vessel walls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What clinical symptoms are most compatible with the disease process seen in the picture?

a) Dementia, social disinhibition
b) Memory loss, language deficits, visuospatial impairment
c) Acute course of hypersalivation, hydrophobia, encephalopathy & death
d) Writhing fluid movements, ataxia, psychosis
e) Parkinsonism, hallucinations, neuroleptic sensitivity

A

Rabies

= Negri Bodies

c) Acute course of hypersalivation, hydrophobia, encephalopathy & death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the pathology pictured?

A

Negri Bodies

seen in Rabies

Acute course of hypersalivation, hydrophobia, encephalopathy & death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What clinical symptoms are most compatible with the disease process seen in the picture?

a) Dementia, social disinhibition
b) Memory loss, language deficits, visuospatial impairment
c) Acute course of hypersalivation, hydrophobia, encephalopathy & death
d) Writhing fluid movements, ataxia, psychosis
e) Parkinsonism, hallucinations, neuroleptic sensitivity

A

Pick’s Disease (FTD)

a) Dementia, social disinhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What clinical symptoms are most compatible with the disease process seen in the picture?

a) Dementia, social disinhibition
b) Memory loss, language deficits, visuospatial impairment
c) Acute course of hypersalivation, hydrophobia, encephalopathy & death
d) Writhing fluid movements, ataxia, psychosis
e) Parkinsonism, hallucinations, neuroleptic sensitivity

A

Caudate Atrophy

seen in Huntington’s Disease

d) Writhing fluid movements, ataxia, psychosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Man presented with visual hallucinations and altered mentation for 6 months before becoming bed-bound. A brain biopsy was conducted. What statement about the patient’s disease is most accurate?

a) It’s treatable w/ PCN
b) Immunosuppression is a primary risk factor for this
c) The patient had signs of Parkinsonism
d) This disease was caused by a tick
e) CSF would likely reveal 14-3-3 positivity

A

Spongiform change - prion disease

e) CSF would likely reveal 14-3-3 positivity

spongiform change, gliosis, & neuronal loss = classic triad

Misfolding maybe induced by mutation or exposure of normal cellular prion protein to pathogenic prions;

Misfolding alters 2ndary structure so that the protein becomes highly resistant to chemical or thermal methods of sterilization.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

36YOF s/p gastric bypass who 3 months later developed confusion, feeling off balanced and shaky eyes. Her brain biopsy is shown.

  1. What did she have?
  2. What could have prevented her symptoms?
  3. What structure was affected?
  4. What nucleus of the thalamus is the damage connected to?
A

Wernicke’s Encephalopathy

Thiamine intake

Mammillary Bodies

Anterior Nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the alpha-synucleinopathies?

A 
L = LBD
A = alpha synucleinopathies
M = MSA
P = PD

All the rest are tauopathies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q
  1. What region of the brain is most often affected in dementia with Lewy bodies?
  2. What regiong of the brain is most often affected in Alzheimer disease?
A
  1. Posterior parietal-occipital functional defect
  2. Temporal parietal functional defect

RITE COPY (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions