Bone and Soft Tissue infection 2 Flashcards

1
Q

Route of infection of acute septic arthritis

A
  • Direct invasion
  • Eruption of bone abscess
  • Haematogenous
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2
Q

3 examples of direct invasion

A
  • Penetrating wound (iatrogenic e.g. joint injection)
  • Intra-articular surgery
  • Arthroscopy
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3
Q

Difference of septic arthritis and osteomyelitis

A
  • Septic arthritis = Inside joint capsule

- Osteomyelitis = Outside joint capsule

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4
Q

3 common organisms that cause septic arthritis

A
  • Staph aureus
  • Strep pyogenes
  • E. coli
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5
Q

Pathology of septic arthritis

A
  • Acute synovitis with purulent joint effusion
  • Articular cartilage attacked by bacterial toxin and cellular enzyme
  • Complete destruction of the articular cartilage
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6
Q

Outcome of septic arthritis

A
  • Complete recovery
  • Partial loss of articular cartilage + subsequent OA
  • Fibrous or bony ankylosis (joint stiffness)
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7
Q

Appearance of acute septic arthritis in a neonate

A

-Irritability
-Resistant to move
-Ill
Picture of septicaemia

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8
Q

Appearance of acute septic arthritis in a child

A
  • Acute pain a single large joint
  • Reluctant to move joint
  • Increased temp, + HR
  • Tenderness
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9
Q

Appearance of acute septic arthritis in an adult

A
  • Often involves superficial joints (knee, ankle, hipe)

- Rare in a healthy adult

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10
Q

Investigations for acute septic arthritis

A
  • FBC, WBC, ESR, CRP, blood cultures
  • X-ray
  • Ultrasound
  • Aspiration
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11
Q

Most common cause of acute septic arthritis in adults

A
  • Infected joint replacement

- Staph. aureus most common organism responsible

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12
Q

DDx for acute septic arthritis

A
  • Acute osteomyelitis
  • Trauma
  • Irritable joint
  • Haemophilia
  • Gout
  • Rheumatic fever
  • Gaucher’s disease
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13
Q

Treatment of acute septic arthritis

A
  • General supportive measures
  • Antibiotics
  • Surgical drainage + lavage (emergency, “never let the sun set on pus”,
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14
Q

2 types of lavage

A
  • Open

- Arthroscopic

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15
Q

3 classifications of TB related to orthopaedics

A
  • Extra-articular (epiphyseal/bones with haemodynamic marrow)
  • Intra-articular (large joints)
  • Vertebral body
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16
Q

Clinical features of orthopaedic TB

A
  • Insidious onset & general ill health
  • Contact with TB
  • Pain (esp. at night) + weight loss
  • Low grade pyrexia
  • Joint swelling
  • Decreased ROM + ankylosis
  • Deformity
17
Q

Pathology of TB

A
  • Primary complex (in lung or gut)
  • Secondary spread
  • Tuberculous granuloma
  • n.b. role of nutrition/other diseases (HIV/AIDS)
18
Q

Presentation of spinal TB

A
  • Little pain

- Present with abscess or kyphosis

19
Q

How to diagnose TB

A
  • Long Hx
  • Involvement of a single joint
  • Marked muscle wasting +marked thickening of synovium
  • Periarticular osteoporosis
20
Q

TB investigations

A
  • FBC, ESR
  • Mantoux test
  • Sputum culture
  • X-ray
  • Joint aspiration + biopsy
21
Q

What is show on a TB X-ray

A
  • Soft tissue swelling
  • Periarticular osteopenia
  • Articular space narrowing
22
Q

DDx for TB

A
  • Transient synovitis
  • Monoarticular RA
  • Haemorrhagic arthritis
  • Pyogenic arthritis
23
Q

Treatment for TB

A
  • Initially = Rifampicin, Isoniazid, Ethambutol for 8 weeks
  • Then = Rifampicin + isoniazid for 6-12 months
  • Rest + splintage
  • Operative drainage rarely necessary