S1: Adrenergic System Flashcards
1
Q
What is the direct regulation of adrenergic transmission?
A
Drugs that act at adrenoreceptors
2
Q
What is the indirect regulation of adrenergic transmission?
A
Drugs that act at altering release/termination of transmission
3
Q
How is noradrenaline converted to adrenaline?
A
PNMT (phenylethanolamine-N-methy transferase)
It is found in the adrenal medulla which is the main site for adrenaline release
4
Q
What does cocaine/tricyclic antidepressant (imipramine) do?
A
- Inhibits uptake transporters
- Increases adrenergic transmission
5
Q
What does MAO inhibitor e.g. Moclobemide do?
A
It is an antidepressant
-increases adrenergic transmission to the brain
