sympathetic pharmacology Flashcards
1
Q
how is the structure of ganglionic neurones in sympathetic system?
A
preganglionic: short
postganglionic: long
2
Q
what receptors mediate sweat gland activity?
A
mAchRs
3
Q
are beta receptors innervated?
A
beta 1 receptor: innervated
beta 2: not innervated, responds to circulating adrenaline
4
Q
where are beta receptors located?
A
beta1: heart, juxtaglomerular apparatus, adipose tissue
beta 2: located in bronchial smooth muscle, uterine smooth muscle, skeletal muscle vasculature
5
Q
what are metabolic effects of adrenoceptors?
A
mainly beta2: activates adenylate cyclase
causes liver to convert glycogen to glucose and muscle to convert glycogen to lactic acid
6
Q
describe alpha receptors
A
a1: post junctional heteroreceptor
a2: pre junctional autoreceptor
