Prosopagnosia Flashcards

1
Q

DeHann, Young & Newcombe, 1987

A

Patient PH: associative prosopagnosia. Could match to FRU but not PIN

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2
Q

Schweinberger (1998)

A

Identity can affect expression judgements

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3
Q

Bauer 1984; Tranel & Damasio 1985

A

PPAs = higher SCRs to familiar faces

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4
Q

Bate 2010

A

Oxytocin improves face recognition in DPs. Modulates distributed face processing network, particularly the amygdala

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5
Q

Domes 2010

A

Oxytocin modulates FFA in face emotion processing task

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6
Q

Haxby 2000

A

OFA = initial visual face processing, FFA = facial identity, STS = changeable aspects e.g. emotion

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7
Q

Delvenne 2004

A

Associate PPA was actually perceptual

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8
Q

Avidan 2014

A

DPs = no composite effect

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9
Q

Duchaine 2006

A

Edward = no face inversion effect

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10
Q

Barton 2009

A

Apperceptive PPAs: configural deficit (for face stimuli and dot patterns) - although some evidence of whole-object processing

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11
Q

Lobmaier 2010

A

DPs = disrupted face-specific, configural processing (impaired for blurred faces but not blurred objects or scrambled faces etc)

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12
Q

Van Belle 2010

A

Acquired PPA = patient PS had abnormal eye gaze exploration patterns so reflects feature-based processing approach

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13
Q

Biotti 2017

A

Highly significant composite effect in DPs

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14
Q

Yovel & Duchaine 2006

A

PPAs impaired for both shapes and features and spacing between them

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15
Q

Witthoft 2016

A

DPs had smaller pRF sizes in ventral face network that rarely extended to ipsilateral or peripheral VF = impaired spatial integration of facial features

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16
Q

Johnston and Morton 1991

A

Babies innate ability to attend to faces

17
Q

Farah 1995

A

Faces = within-category so harder. But not just due to this as created OR task of comparable difficulty and PPAs still worse at faces

18
Q

Moscovitch 1997

A

CK: visual agnosia but no PPA

19
Q

Sergent and Signoret 1992

A

RM Impaired for faces but not cars

20
Q

McNeill and Warrington 1993

A

WJ PPA for human faces but not sheep faces

21
Q

Duchaine and Yovel 2006

A

Edward (DP) = impaired at faces but not within-category objects so mechanisms for each = separate developmental processes

22
Q

Rangarajan 2014

A

EBS to right FFA only = deficits in conscious face perception e.g. distortion of faces, while left FFA = non-face related aspects e.g. colour changes

23
Q

Jonas 2014

A

EBS to right (but not left) OFA = impaired face discrimination

24
Q

Hadjikhani 2002

A

PPAs (1 DP, 2 AP) did not show normal increase in FFA or OFA fMRI activation in response to faces (objects and faces had similar activation)

25
Q

Avidan 2005

A

DPs showed normal FFA activation (although could be disconnection syndrome? Could be continuum?)
FFA detection only, full recognition requires activation of anterior temporal semantic stores.
But: Grill-Spector 2004. Could be feedback mechanisms?

26
Q

Dalrymple 2011

A

No N170 if both OFA and FFA. Spared if only bilateral FFA damaged. Also patient with only STS damage only showed impairment when expression changed. So need at least two components of FP network spared?

27
Q

Schiltz 2006

A

Damaged OFA = reduced responses in FFA (feedback)

28
Q

Barton 2003

A

Posterior occipital lesions = perceptual deficits (impaired structural and matching to FRUs), anterior temporal = can’t extract semantic info (match to PIN)

29
Q

Gomez 2015; Song 2015

A

DPs had abnormal white matter around FFA so disconnection syndrome?

30
Q

Renzi 2013

A

Right DLPFC is involved in holistic processing. DPs show higher fMRI activity in this area = compensatory (but ineffective) mechanism?

31
Q

Cattaneo 2016

A

Polymorphisms in OXTR associated with DP

32
Q

Fisher 2017

A

DPs = attenuated N250 in identity matching task.

Identity-specific deficit.

33
Q

Johnen 2014

A

Family of DPs: all showed varying severity of PPA and general visual deficits.
Continuum!

34
Q

Avidan & Behrmann 2008

A

DPs better at familiar face matching than unfamiliar.

= covert recognition

35
Q

Eimer 2012

A

DPs had intact N250 (occipito-temporal) for non-recognised famous faces, but no P600f.
Suggests disconnection between intact identity-specific memory and later semantic stages, which are necessary for full FR.

36
Q

Grill-Spector 2004

A

Differential FFA activation for face detection vs face identification tasks.

37
Q

Barton 2003

A

Anterior temporal lesions = worse at task involving extraction of long-term memory representations / mental imagery.