Movement Disorders Flashcards
What drugs may unmask an underlying chorea (huntingtons)
Dopaminergic drugs (L-dopa, bromocriptine, and lisuride)
Tardive dyskinesia may be a side effect of what drug used to suppress chorea in parkinsons
haloperidol
and other dopamine antagonists
What recreational drug of abuse may cause rapid development of Parkinsonism
MTPT
Trihexyphenidyl has what mechanism of action? why is it used in Parkinsonism?
anticholinergic
used to decrease signs of parkinsonism caused drugs that interfere with dopamine neurotransmission. (offending medication should also be slowly tapered off too)
What medications are used to treat Torettes?
Haloperidol, pimozide, trufluoperazine, and fluphenazine.
anti-epileptics such as carbamazepine and phenytoin are not useful
What is Meige syndrome?
what drug can produce the features of Meige syndrome?
what is a common treatment
focal dystonia characterized by blepharospams, forceful jaw opening, lip retraction, neck contractions, and tongue thrusting.
sometimes brought on by phenothiazine or butyrophenone
botox injections
what’s another name/description for Wilson’s disease?
how does it affect the kidney/liver?
Hepatolenticular degeneration
renal tubular acidosis occurs as well as hepatic fibrosis–>hepatic failure
In vegetative state what brain structures are injured and what remains intact?
cortex is injured and brainstem remains intact
combo of increased calcium, fatigue, weakness, and pseudogout in an elderly patient should raise suspicion of what?
Primary hyperparathyroidism.
even if calcium levels are normal with these symptoms, PTH may be elevated
