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Biochemistry S2 > Protein Digestion FC > Flashcards

Protein Digestion FC Flashcards

1
Q

Questions

A

Answers

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2
Q

Where does most protein digestion occur?

A

Small intestine

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3
Q

Which cells secrete HCL? Which cells secrete pepsinogen?

A

Parietal cells - HCL

Chief cells - pepsinogen

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4
Q

What ion exchange occurs when H+ enters the gastric pit? When Cl- enters the pit?

A

K+ moves into parietal cell when H+ moves into pit

K+ transported out of cell with Cl-

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5
Q

What compound is removed from the parietal cell? What takes its place? What does this cause in the blood stream?

A

HCO3-
Cl-
Alkaline Tide

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6
Q

What is the main purpose of HCL?

A

Denature proteins to make them more accessible for proteases

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7
Q

Which two hormones stimulate secretion of pepsinogin and HCl?

A

Histamine and gastrin

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8
Q

Which two hormones stimulate secretion of pancreatic digestive pro-enzymes and enteropeptidase? Where is enteropeptidase located?

A

Cholecystokinin
Secretin
Villi

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9
Q

What are three major pancreatic pro-enzymes? What activates each into active form?

A

Trysinogen - enteropeptidase
Chymotrysinogen - trypsin
Procarboxypeptidase - trypsin

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10
Q

What two amino acids does trypsin act on?

A

Arginine and lysine

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11
Q

What 5 amino acids does chymotrypsin act on?

A

Tryptophan, Tyrosine, Phenylalanine, Methionine, Leucine

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12
Q

What 3 amino acids does elastase act on?

A

Alanine, glycine, serine

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13
Q

What are three brush border peptidases? What do they produce?

A

Endopeptidase, aminopeptidase, dipeptidase

Free AA and di/tri AA

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14
Q

What is transported into cell with FAA? With di/tri?

A

FAA - Na+

Di/tri - H+

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15
Q

How to FAA diffuse into blood stream?

A

Passively

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16
Q

What maintains Na+ concentration in mucosal cell?

A

Na+/K+ atpase pump, pumps Na+ out into blood

17
Q

What are the essential AA? PVT TIM HALL

A 
Phenyalanine
Valine
Threonine
Tryptophan
Isoleucine
Methionine
histidine
Arginine (only in children)
Leucine
Lysine
18
Q

What is Hartnup Disease?

A

Defect transportine neutral AA across intestine

19
Q

What is Cystinuria?

A

Congenital defect tranporting cystine

20
Q

What causes a food allergy?

A

Proteins enter circulation, provoking formation of antibodies

Biochemistry S2 (13 decks)

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