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Pharmocology - Joy > Macrolides > Flashcards

Macrolides Flashcards

1
Q

Semisynthetic derivatives of erythromycin

A

Azithromycin

Clarithromycin

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2
Q

2 sugars of erythromycin

A

Desosamine

Cladinose

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3
Q

Drugs under macrolides

A

Erythromycin
Clarithromycin
Azithromycin
Ketolides

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4
Q

Erythromycin is fairly stable at what temperature

A

4 degrees celcius (loose activity at 20 degrees and at acid pH)

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5
Q

Drug of choice for corynebacterial infections

A

Erythromycin

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6
Q

T/F erythromycin is not removed by dialysis

A

True

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7
Q

Recommended prophylaxis against endocarditis during dental procedures in individuals with valvular heart disease

A

Erythromycin (but replaced by clindamycin)

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8
Q

Major metabolite of clarythromycin

A

14 hydroxyclarithromycin

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9
Q

A macrolide that may be associated with a small increased of cardiac death

A

Azithromycin

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10
Q

Give the drug sub class of ketolide

A

Teithromycin

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11
Q

A chlorine-substituted derivative of lincomycin, an antibiotic that is elaborated by Streptomyces lincolnensis

A

Clindamycin

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Pharmocology - Joy (5 decks)

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