Vaccines

Question 1

whole organism vaccine

Answer 1

Rabies, Hep A, IM poliovirus, Influenza
plague, cholera, parathyphoid fever
(RIP Ha)
Th2 only

Question 2

Live attenuated

Answer 2

MMR, oral polio, Varicella zoster, rotavirus, BCG, yellow fever,
intranasal flu

Th1 and Th2

Question 3

Live heterologous

Answer 3

enough antigenic similarity between small pox and vaccinia that the vaccinia provdies long term protection against smallpox

Question 4

toxoid

Answer 4

Diphtheria, tetanus, botulism

exotoxin turned into toxoid. requires boosters. Ab response

Question 5

polysaccharides

Answer 5

meningococcal, pneumococcal, haemophilus flu type B, tyhoid fever

take away the capsule and thats what you inject

Question 6

subviron

Answer 6

influenza

degrades the envelope which results in exposure of subvirion and thats what you inject

Question 7

recombinant vaccine

Answer 7

Hep B
HPV

molecular biology is used to make it look like theres genetic material in there but theres really not.

Question 8

Alum

Answer 8

adjuvant that makes vaccine stay local by producing a depot and causes irritation to increase response

Question 9

Formalin

Answer 9

cross-links amino and amide groups of proteins. often used to make toxoids

Question 10

beta-propiolactone

Answer 10

cross-links nucleic acid chains and kills without affecting antigenic structure

Question 11

physical inactivation

Answer 11

UV light, heat, gamma irradiation

Question 12

preservatives

Answer 12

benzalkonium chloride, formaldehyde