Gynaecological Problems 2 Flashcards

1
Q

What are some of causes of intermenstrual bleeding?

A

Pregnancy related (ectopic/GTD)
Physiological (spotting around ovulation)
Vaginal - vaginitis, tumours, adenosine
Cervical - STI, cancer, polyps, ectropion
Uterine - fibroids, polyps, cancer, adenomosis, endometriosis
Oestrogen-secreting ovarian cancers
Iatrogenic - tamoxifen, after a smear/treatment to cervix, missing OCP, drugs affecting clotting

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2
Q

What investigations should be used for intermenstrual bleeding?

A
pregnancy test 
infection screen - chlamydia 
cervical smear only if due 
FBC, clotting, TFT 
transvaginal US to look for abnormality
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3
Q

How would you manage inter menstrual bleeding if you suspected cancer?

A

full pelvic examination

incl cervical speculum examination and refer

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4
Q

How would you manage inter menstrual bleeding if you suspected infection?

A

abx depends on organism involved and contact tracing

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5
Q

How you you manage inter menstrual bleeding when hormonal contraception is used?

A

unscheduled bleeding in first 3 months after starting a new hormonal contraceptive method

speculum +/- bimanual examination if beyond 3 months, no change in symptoms

reassurance/medical treatment if findings normal, no other symptoms + woman >45

If beyond 6 months or no contraceptive use then US

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6
Q

What is cervical ectropian?

A

glandular/columnar cells from the ‘inside’ of the cervical canal are present on the ‘outside’ of the vaginal portion of the cervix which contains squamous cells

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7
Q

How is inter menstrual bleeding due to cervical ectropion treated?

A

may resolve spontaneously if COCP is stopped or after pregnancy

can be managed conservatively or cauterised with silver nitrate therapy

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8
Q

How is intermenstrual bleeding due to polyps treated?

A

avulse and send for histology

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9
Q

How are fibroids treated when causinng inter menstrual bleeding?

A

small fibroids are removed hysteroscopically
uterine artery embolism
drugs that reduce oestrogen levels
larger fibroids can be treated with drugs

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10
Q

What is post coital bleeding?

A

vaginal bleeding after intercourse that is not menstrual loss (must exclude cervical carcinoma unless first intercourse)

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11
Q

What are the causes of post coital bleeding?

A

cervical carcinoma
cervical ectropion
cervical polyps
cervicitis/vaginitis

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12
Q

What are the basic investigations for post coital bleeding?

A

inspect cervix and smear
if polyps evident - avulse and send for histology
if smear normal treat ectropion with cryotherapy
if not coloscopy to exclude malignancy

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13
Q

What are the causes of menstrual irregularity?

A
Anovulatory cycles common just after menarche or before menopause
Fibroids
Uterine + cervical polyps
Adenomyosis
Ovarian cysts
Chronic pelvic infection
Ovarian/cervical malignancy
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14
Q

How should menstrual irregularity be investigated?

A

haemoglobin
cervical smear
US exam of cavity (if >35 years)
endometrial biopsy (if thickened, in >40s)

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15
Q

How is menstrual irregularity managed if no anatomical cause?

A

IUS or COCP - regular and lighter menstruation

Progesterones - amenorrhoea but bleeding following withdrawal

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16
Q

What are the causes of menorrhagia?

A
subtle abnormalities of endometrial haemostats or uterine prostaglandin levels 
uterine fibroids 
polyps
chronic pelvic infection 
ovarian tumour 
endometrial and cervical malignancy 
thyroid disease 
homeostatic disorders 
anticoagulant therapy 
coagulopathy
17
Q

How is menorrhagia treated?

A

1) IUS - progesterone imprinted
2) antifibrinolytics, NSAIDS, COCP
3) progesterones, GnRH analogies
4) surgical - polyp removal, endometrial ablation, resection of fibroid

18
Q

What is primary dysmenorrhoea?

A

when no organic cause found

usually coincides with the start of menstruation and very common

19
Q

What is secondary dysmenorrhoea?

A

pain precedes and is relived by onset of menstruation

often with irregular bleeding, menorrhagia and dyspareunia

20
Q

What are the causes of secondary dysmenorrhoea?

A
fibroids
adenomyosis 
endometriosis 
PID 
ovarian tumours
21
Q

How should dysmenorrhoea be investigated?

A

pelvic US

laparoscopy

22
Q

How is primary dysmenorrhoea managed?

A

NSAIDS

COCP

23
Q

What is primary amenorrhoea?

A

menstruation not started by 16

24
Q

What is secondary amenorrhoea?

A

previous normal menstruation ceases for >6 months

25
Q

What are the physiological causes of amenorrhoea?

A

pregnancy
after menopause
occ during lactation

26
Q

What are the hypothalamic hypogonadism causes of amenorrhoea?

A

low weight
anorexia
excessive exercise
tumours

27
Q

What are the other causes of amenorrhoea?

A
hyperprolactinaemia 
thyroid - under or over active 
PCOS
turners syndrome 
congenital problems (imperforate hymen) 
cervical stenosis 
drugs 
congenital abnormalities
28
Q

How is amenorrhoea investigated?

A
pregnancy test 
FSH and LH measured 
Prolactin levels 
Total testosterone and sex hormone binding globulin 
TFTs 
Pelvis US
29
Q

How is amenorrhoea managed?

depends on cause

A
fertility clinic referral 
contraception 
HRT if premature ovarian failure 
surgery if structural abnormalities 
bone protection 
treat turners with OCP and growth hormone