Autoantibodies Flashcards

1
Q

Anti-ACh receptor

A

Myasthenia gravis

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2
Q

Anti-basement membrane

A

Goodpasture syndrome (lungs and kidneys)

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3
Q

Anti-Cardiolibin

Lupus Anti-Coagulant

A

SLE

Anti-Phospholipid Syndrome

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4
Q

Anti-Centromere

A

Limited Scleroderma (CREST syndrome)

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5
Q

Anti-Desmosome

Anti-Desmoglein

A

Pemphigus vulgaris

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6
Q

Anti-dsDNA

A

“Anti-Smith”

SLE

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7
Q

Anti-Smith

A

“Anti-dsDNA”

SLE

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8
Q

Anti-glutamic acid decarboxylase (GAD-65)

A

Type 1 DM

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9
Q

Anti-Hemidesmosome

A

Bullous pemphigoid

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10
Q

Anti-Histone

A

DRUG-induced Lupus

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11
Q

Anti-Jo-1

A

Polymyositis/Dermatomyositis
“Anti-SRP”
“Anti-Mi-2”
“Anti-Hystidyl tRNA”

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12
Q

“Anti-Hystidyl tRNA”

A

Polymyositis/Dermatomyositis
“Anti-SRP”
“Anti-Mi-2”
Anti-Jo-1

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13
Q

Anti-Microsomal

A

Hashimoto thyroiditis

Anti-Thyroglobulin

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14
Q

Anti-thyroglobulin

A

Hashimoto thyroiditis

Anti-Microsomal

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15
Q

Anti-Mitochondrial

A

Primary Biliary Cirrhosis

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16
Q

Anti-Nuclear Antibodies

A

SLE

Non-specific

17
Q

Anti-Parietal Cell

A

Pernicious anemia

18
Q

Anti-Scl-70

A

Scleroderma (diffuse)

Anti-DNA Topoisomerase I)

19
Q

Anti-DNA Topoisomerase I

A

Scleroderma (diffuse)

Anti-Scl-70

20
Q

Anti-Smooth Muscle

A

Autoimmune hepetitis

21
Q

Anti-SSA

A

Sjogren Syndrome
Anti-SSB
Anti-Ro
Anti-La

22
Q

Anti-Ro

A

Sjogren Syndrome
Anti-SSA
Anti-Ro
Anti-La

23
Q

Anti-TSH receptor

A

Graves Disease

24
Q

Anti-U1 RNP (Ribo nucleo protein)

A

Mixed Connective Tissue Disease

25
Q

IgA anti-endomysial

A

Celiac Disease

IgA anti-tissue transglutaminase

26
Q

IgA anti-Tissue transglutaminase

A

Celiac Disease

IgA Anti-endomysial

27
Q

MPO-ANCA

A

p-ANCA
Microscopic Polyangiitis
Eosinophillic Granulomatosis with Polyangiitis (Churg Strauss Syndrome

28
Q

p-ANCA

A

MPO-ANCA
Microscopic Polyangiitis
Eosinophillic Granulomatosis with Polyangiitis (Churg Strauss Syndrome

29
Q

PR3-ANCA

A

c-ANCA

Granulomatosis with Polyangiitis (Wegner)

30
Q

c-ANCA

A

PR3-ANCA

Ganulomatosis with Polyangiitis (Wegner)

31
Q

Rheumatoid Factor

A

IgM Ab against IgG Fc region

Anti-CCP (more specific) anti citrullinated protein antibodies

32
Q

Anti Citrullinated Protein antibodies

A

Rheumatoid Factor

IgM Ab against IgG Fc region