Chlorpromazine Flashcards

1
Q

what is Chlorpromazine

A

A phenothiazine-based antipsychotic

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2
Q

what is Chlorprozamine an antagonist on

A

on dopaminergic-receptors (subtypes D1, D2, D3 and D4), serotonergic-receptors (5-HT1 and 5-HT2),histaminergic-receptors (H1-receptors), alpha1/alpha2-receptors and muscarinic (cholinergic) M1/M2-receptors

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3
Q

what are chlorpromazine antipsychotic actions are due to

A

long-term adaptation by the brain to blocking dopamine receptor

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4
Q

is chlorpromazine still used as anti-psychotic drug

A

no

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5
Q

what is Chlorpromazine has several other actions and therapeutic uses

A

including as an antiemetic and in the treatment of intractable hiccup

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