hormones in menstruation and pregnancy Flashcards

1
Q

what are the two phases of menstrual cycle

A

follicular

luteal

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2
Q

what hormone stimulates follicular development

A

FSH

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3
Q

what secretes FSH and LH

A

anterior pituitary

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4
Q

what hormone stimulates FSH and LH to be released and where does it come from

A

GnRH from hypothalamus

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5
Q

what does the follicle secrete

A

oestrogen

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6
Q

what effect does oestrogen have on FSH

A

negative feedback - increasing oestrogen decreases FSH

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7
Q

what effect does oestrogen have on LH

A

positive feedback - increasing oestrogen increases LH

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8
Q

what is ‘LH surge’

A

peak conc of LH which stimulates ovulation

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9
Q

effect of LH on follicle

A

causes it to release oocyte

promotes formation of corpus luteum

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10
Q

what does corpus luteum secrete

A

progesterone (and some oestrogen)

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11
Q

role of progesterone

A
prepares endometrium for implantation 
maintains endometrium in early pregnancy 
increases basal body temp
relaxes smooth muscle 
produces thick cervical mucous
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12
Q

if no implantation occurs, what happens

A

triggers corpus luteum regression

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13
Q

effect of corpus luteum regression

A

decreased progesterone and oestrogen conc

increase in FSH conc

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14
Q

if implantation occurs, what hormone signals corpus luteum to stay alive

A

HCG produced by placenta

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15
Q

what other hormones does placenta produce

A

HCS - promotes protein tissue formation (breast enlargement)
progesterone
oestrogen

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16
Q

after birth, what does decreased oestrogen production cause

A

increase in prolactin - prepare for breastfeeding

17
Q

role of oestrogen

A

endometrial thickening
produces thin cervical mucous
increased sodium and water reabsorption in kidneys
increased water conc in uterus

18
Q

what hormonal changes occur in pregnancy

A
diabetic (increased insulin resistance)hyperparathyroid
hyperthyroid
hyperoestrogenic
hyperprogesterogenic
hypertensive
19
Q

effect of progesterone in pregnant ladies

A

development of decidual cells
decreases uterus contractility
preparation for lactation

20
Q

effect of oestrogen in pregnant ladies

A

enlargement of uterus
breast development
relaxation of ligaments

21
Q

what does the estriol level indicate

A

if high, may indicate congenital abnormalities e/g/ down’s syndrome

22
Q

when does ovulation occur

A

14 days before next menses

23
Q

how long before ovulation does LH surge occur

A

24-36 hours

24
Q

how quick and by how much does HCG increase

A

doubles 50% in 48 hours