Green - Salivary Secretion, Swallowin, And The Esophagus Flashcards

1
Q

Failure of the lower esophageal sphincter to relax, resulting in difficulty in swallowing

A

Achalasia

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2
Q

Saclike dilation in the salivary gland where the initial saliva is formed

A

Acinus

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3
Q

Difficulty in swallowing

A

Dysphagia

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4
Q

Part of the salivary gland that connects the striated duct to the acinus

A

Intercalated duct

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5
Q

Change in the type of cell in a tissue from normal to abnormal

A

Metaplasia

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6
Q

First contraction in esophagus after food enters, initiated by swallowing

A

Primary perstaltic contraction

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7
Q

Subsequent contraction of esophagus ; initiated by presence of food

A

Secondary peristaltic contraction

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8
Q

Part of the salivary gland that opens into the mouth, this is where the ionic composition of the saliva is modified with sodium reabsorption and secretion of K and HCO3

A

Striated duct

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9
Q

Dry moth due to lack of saliva

A

Xerostomia

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10
Q

Functions of salivary secretion

A

Digestion

Lubrication

Protection

(Sense of taste also depends on adequate saliva)

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11
Q

Saliva starts the digestions of ?

A

Starches and fats

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12
Q

Located in the acinus and intercalated cells ________ contract when saliva production is stimulated and eject saliva into the mouth

A

Myoepithelial cells

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13
Q

Saliva production is ______ by parasympathetic stimulation and _______ by sympathetic stimulation

A

Increased

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14
Q

Production of saliva is decreased by ?

A

Sleep, fatigue, fear, dehydration, anticholinergic drugs

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15
Q

What does parasympathetic stimulation do in regards to saliva production ?

A

Increases saliva production by :

Increasing transport process of acinar and ductal cells

Vasodilation of blood vessels

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16
Q

What does sympathetic stimulation do in regards to saliva production?

A

Increases saliva production by; ‘

Transiently increase production of saliva and growth of salivary glands

Cause contraction of myoepithelial cells

Constriction of blood vessels

17
Q

Saliva is an ultrafiltrate of plasma and is _____tonic to plasma

A

Hypotonic

18
Q

Proteins found in saliva

A

Alpha-amylase

Lingual lipase

Mucin

Epidermal and nerve growth factors

19
Q

What are the contents of saliva

A

Water

Ions

Protein

Bacteriocidal substances

Electrolytes

Organic compounds

20
Q

Striated ducts reabsorb what ions?

A

Na

Cl

21
Q

Striated ducts secrete what ions?

A

K+

HCO3-

22
Q

High flow rates affect the ion concentration in saliva because there is less time for ion movement. Therefore, at higher flow rates, saliva is more ______

A

Isotonic

23
Q

Bicarb concentration in saliva ______ w/ increasing flow because its secretion is _________ when salivation stimulated

A

Increases

Stimulated

24
Q

Increased saliva flow rates causes a _____ in Na concentration

A

Increase

25
Q

Increased saliva flow causes a ______ in Cl concentration

A

Increase

26
Q

Increased saliva flow rate causes a ______ in K concentration?

A

Initial decrease then plateau

27
Q

Increased saliva flow rate causes Bicarb concentration to _______

A

Increase then plateau

28
Q

Xerostomia is associated with ?

A

Dental caries and chronic infections of the buccal mucosa;

Speech taste swallowing dysfunction

Antidepressants (which have anticholinergic effect)

Diseases such as Sjogren’s syndrom

Radiation damage during therapy for head and neck tumors

29
Q

Deglutition

A

Swallowing

30
Q

Lesions in the swallowing center of the medulla result in loss of ______ phase of swallowing and may result in aspiration

A

Pharyngeal

31
Q

Formed by cricopharyngeal muscle; separates esophagus from oral cavity and prevents entry of air.

A

Upper esophageal sphincter

32
Q

Not a distinct muscle but does have increased pressure compared to rest of esophagus.

Separates esophagus from stomach and prevents the entry of gastric acid into the esophagus

A

Lower esophageal sphincter

33
Q

Primary peristaltic contraction is initiated by

A

Swallowing

34
Q

Secondary peristaltic contractions are initiated by ?

A

The presence of food in the esophagus

Triggered by mechanoreceptors stretch

Mediated by enteric nervous system and vagovagal reflexes

35
Q

Neuromuscular disorder of the lower 2/3 of esophagus, leading to absence of peristalsis and failure of LES to relax

Food accumulates in esophagus taking hours to enter stomach and causing esophageal dilation

S/s; dysphagia, regurgitation of ingested food, and weight loss

Treated w/ drugs, endoscopic procedures, or surgery to relax LES

A

Achalasia

36
Q

Eructation

A

Belching