Clostridium difficile infection and other clostridial infections

Question 1

CDI=

Answer 1

Clostridium difficile infection

Question 2

Clostridium difficile:

Answer 2

• obligately anaerobic
• gram-positive
• spor-forming bacillus

Question 3

Clostridium difficile infection (CDI):

Answer 3

Clostridium difficile infection is a colonic disease

Question 4

Clostridium difficile infection (CDI) - Causes:

Answer 4

It is consequence of C.difficile spores ingestion

Question 5

Clostridium difficile infection (CDI) - Pathogenesis:

Answer 5

1. exposure to antibiotics
2. susceptible patient acquires toxigenic strain of C.difficile
3. asympomatic colonization or CDI if inadequate IgG response