Introduction Flashcards

1
Q

How much will the population grow between 2015 to 2020?

A

By 3%

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2
Q

Between 2015 to 2020 how much will the populations of a) over 65
b)over 85
grow by?

A

a) 12%

b) 18%

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3
Q

What are the two theories of developmental biology?

A

Aristotle and Epigenesis

Nicolas Hartsoeker and Preformatisation

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4
Q

What is the preformatisation theory?

A

The belief that organisms develop from miniature versions of themselves
ie the homunculus = little man

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5
Q

Who proposed the cell theory?

A

Robert Hooke 1665

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6
Q

What are the three parts to the cell theory?

A

1) All organisms are composed of one or more cells
2) The cell is the most basic unit of structure, function and organisation of all organisms
3) All cells arise from pre-exisiting cells

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7
Q

Who proposed the germ plasm determinants theory?

A

Friedrich Leopold August Weismann 1880s

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8
Q

What are the 2 main types of cells?

A

Germ cells and somatic cells

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9
Q

Heritable information is transmitted by which cells?

A

Germ cells in the gonads and NOT somatic cells

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10
Q

What are the two types of development?

A

Mosaic and regulative

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11
Q

Who came up with the theory of mosaic development?

A

Weissmann?

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12
Q

What is regulative development?

A

The fate of a cell depends on its interaction with neighbours, not what piece of cytoplasm it has.
A blastomere is isolated early in cleavage to be able to form the whole individual

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13
Q

What is mosaic development?

A

Cell fate is determined by the components of the cytoplasm found in each blastomere

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14
Q

Which experiment shows mosaic development?

A

Roux’ s exeriment on the frog embryo
Half the embryo killed at the 2 cell stage = only half of the embryo develops
The cell was killed but was left in contact with the remaining cell

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15
Q

Which experiment shows regulative development?

A

Dreisch’s experiment on the sea urchin embryo
Separated at the 2 cell stage and the 4 cell stage
2 or 4 smaller larvae develop

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16
Q

What causes asymetric division?

A

Inbalance of cell receptors
Unequal distribution of intracellular proteins
Distribution of extracellular proteins eg in the ECM

17
Q

What are the 3 types of signalling?

A

Paracrine - Between 2 different cells
Autocrine - Between the same cell
Juxtacrine - Contact between two cells eg notch

18
Q

Signals can be either —- or —–?

A

Intrusive

Permissive

19
Q

What are the common features of the cell transduction pathways?

A

Reception
Transduction
Response