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Step1 > Toxins > Flashcards

Toxins Flashcards

1
Q

Related to spoiled dark meat fish

A

Histamine toxin due to scombroid poisoning

Bacerial histidine decarboxylase converts histidine to histamine

mimics anaphylaxis

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2
Q

Pufferfish

A

Tetrodotoxin

binds fast voltage Na channels in cardiac and nerve tissues preventing depolarization

AR: paresthesias, weakness, loss of reflexes

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3
Q

Reef fish

A

Ciguatoxin

opens Na channels causing depolarization

AR: perioral numbness, reversal of hot and cold sensations, heart block

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