Nelson - Ch. 199 Shigella

Question 1

Used to describe diarrhea with fever, abdominal cramps, rectal pain, and mucoid stools

Answer 1

Dysentery

Question 2

Bacillary dysentery is used to distinguish ___ from amebic dysentery caused by E. histolytica

Answer 2

Shigella dysentery

Question 3

4 species of Shigella responsible for bacillary dysnetery

Answer 3

S dysenteriae (serogroup A), S flexneri (serotype B), S boydii (serotype C), and S soneii (serotype D)

Question 4

3rd most important pathogen identified in the Foodborne Disease Active Surveillance Network in the US

Answer 4

Shigella

Question 5

Shigella infection is MC in what age group

Answer 5

2nd-3rd year

Question 6

Approx 70% of all episodes and 60% of all Shigella-related deaths involve what age group

Answer 6

Younger than 5 years

Question 7

T/F Breastmilk from women living in Shigella endemic areas contains antibodies to both virulence and plasmid-coded antigens and lipopolysaccharides

Answer 7

T

Question 8

T/F Asymptomatic shigella infection of children and adults occurs commonly in endemic areas

Answer 8

T

Question 9

MCC of bacillary dysentery in preindustrial societies

Answer 9

S. flexneri

Question 10

2nd MCC of bacillary dysentery in preindustrial societies

Answer 10

S. sonnei

Question 11

Shigella serotype that tends to occur in massive epidemics, although it is also endemic in Asia and Africa, where it is associated with high mortality rates (5-15%)

Answer 11

S. dysenteriae

Question 12

Risk factors for shigella infection

Answer 12

1) Contaminated food (salad or other item requiring extensive handling of ingredients) and water 2) Exposure to both freshwater and saltwater

Question 13

As few as ___ S. dysneteriae serotype 1 can cause dysentery

Answer 13

10

Question 14

Ingestion of ___ Vibrio cholerae is necessary to cause cholera

Answer 14

10^8-10^10