endocrine Flashcards

1
Q

who should levyothyroxine be used in caution with -also indication

A

corticosteroid first with hypopituarism to prevent addinsons crisis

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2
Q

drugs to avoid or be cautious with with levyothyroxine

A

antacids, iron cal salts reduce uptake so leave 4 hour gap
enhance warfarin
increased dose with p450 inducers
insulin may need elevated requirement

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3
Q

key side effect with metformin

A

weight loss
gi upset
LACTIC ACIDOSIS

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4
Q

consideration for in patients with metformin

A

before and after may need to be withheld especcialy if IV contract media for 48 hours

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5
Q

who may need increased dose of insulin

A

those on steroids and loop thiazide diuretics

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6
Q

alodeonic acid ci

A

smokers with dental disease
peptic ulcer- upper gi disorder –> can cause bleeding
HYPOCALAEMIA

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7
Q

SE OF Alodendorooni acid

A
osphagitis
osteonecrosis of jaw 
atypical femur fracture 
hypophosphatemia 
bloating flatulence dyspesisa
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8
Q

key consideration if needing alodreonic acid

A

see dentist before and during

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9
Q

carbimazole SE

A

LMNOP - lymphnodepathy and liver disease, myalgia, neuritis, occasional agranuloatcytosis and pritusus/pyshcosis

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10
Q

avoid carbimazole in

A

preg, breast feeding, lliver disease blood disease

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11
Q

di with carbimazole

A

swet- steroids, warfarin erythromycin and theophyylien

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12
Q

mineracorticoids

A

works by binding to aldosterone recepgtor
used I adrenocoristol insuufficieency such as cortisol and aldosterone defieicency in addisons disease
cause opposite effect of acei
other meds include hydrocoristone

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13
Q

avoid fludrocortione in

A

adrenal suppresininfectionp

psychiatric disorders

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14
Q

uses of calcium and vitamin d

A

hypocalcema
hypovitamin D - rickets and osteomalacia
osteoporosis
ckd- secondary to hyperparhtyodisism ad renal osteodystrophy
hyperkalaemia (with insulin)

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15
Q

se of vitamin c and d analgoues

A

hypercalaccemia

constipation

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16
Q

drug interactions

A

bisophates
Antacids
Levythyroxine and Tetracycline (softening of teeth)
anti convulstant reduce absorption of cal