endocrine Flashcards
who should levyothyroxine be used in caution with -also indication
corticosteroid first with hypopituarism to prevent addinsons crisis
drugs to avoid or be cautious with with levyothyroxine
antacids, iron cal salts reduce uptake so leave 4 hour gap
enhance warfarin
increased dose with p450 inducers
insulin may need elevated requirement
key side effect with metformin
weight loss
gi upset
LACTIC ACIDOSIS
consideration for in patients with metformin
before and after may need to be withheld especcialy if IV contract media for 48 hours
who may need increased dose of insulin
those on steroids and loop thiazide diuretics
alodeonic acid ci
smokers with dental disease
peptic ulcer- upper gi disorder –> can cause bleeding
HYPOCALAEMIA
SE OF Alodendorooni acid
osphagitis osteonecrosis of jaw atypical femur fracture hypophosphatemia bloating flatulence dyspesisa
key consideration if needing alodreonic acid
see dentist before and during
carbimazole SE
LMNOP - lymphnodepathy and liver disease, myalgia, neuritis, occasional agranuloatcytosis and pritusus/pyshcosis
avoid carbimazole in
preg, breast feeding, lliver disease blood disease
di with carbimazole
swet- steroids, warfarin erythromycin and theophyylien
mineracorticoids
works by binding to aldosterone recepgtor
used I adrenocoristol insuufficieency such as cortisol and aldosterone defieicency in addisons disease
cause opposite effect of acei
other meds include hydrocoristone
avoid fludrocortione in
adrenal suppresininfectionp
psychiatric disorders
uses of calcium and vitamin d
hypocalcema
hypovitamin D - rickets and osteomalacia
osteoporosis
ckd- secondary to hyperparhtyodisism ad renal osteodystrophy
hyperkalaemia (with insulin)
se of vitamin c and d analgoues
hypercalaccemia
constipation