Medicine- heme/ onc Flashcards
1
Q
clues to HHT
A
plt decrease by >50%
necrotic lesion at injeciton site
arterial/venous clot
2
Q
gold standard dx for HHT?
A
serotonin release assay
3
Q
tx of HHT
A
STOP HEP
START direct throbmin inhibitor (argibatran)
4
Q
FAT RN mnemonic for TTP
A
fever anemia (MAHA) thrombocytopenia Renal Neuro
5
Q
Multiple Myeloma CRAB
A
M= monoclonal spikes of IgG, A (not M) C= hyperCa R= renal involvement A= anemia B= bone lesions, back pain
6
Q
mechanism of FVleiden
A
cannot bind activated protein C
7
Q
what complication do pernicious anemia patients need to be screened for?
A
gastric cancer
8
Q
treatment of ITP
A
IVIg or glucocorticoids –> observe if only skin manifestations or platelets >30k
9
Q
coombs in hereditary spherocytosis?
A
NEGATIVE
10
Q
“dimorphic RBCs” on smear
A
sideroblastic anemia
11
Q
waldenstrom macroglobulinemia
A
monoclonal M spikes
hypervistcosity sx- diplopia, tinitus, head ache, neuropathy
