STRAT-OG, Contraception Flashcards

1
Q

1 - Evidence suggests that the highest conception rate occurs with intercourse 2 days prior to ovulation

2 - Sperm can survive within the female genital tract for 5–7 days

3 - The ovum is able to be fertilised up to 48 hours following ovulation

4 - Ovulation can be detected by a rise in luteinising hormone

5 - The average conception rate for midcycle intercourse is approximately 15% per cycle

A

1- True

2 - True

3 - The answer is false. It is 12 hours.

4 - The answer is true.

5 - The answer is false. It is 30%.

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2
Q

1 - Consent for termination of pregnancy in under-16-year-old women has to be obtained from a legal guardian

2 - Sexual activity should be discouraged in both men and women with learning difficulties because of the risk of unplanned pregnancy

3 - In England, contraception should not be prescribed to under-16-year old women unless they are deemed to be Fraser competent

4 - Termination of pregnancy always requires the signatures of two independent medical practitioners.

A

1 - The answer is false. This can be obtained from the patient if compliant with Fraser guidelines.

2 - The answer is false. This would contravene human rights.

3 - The answer is true.

4- The answer is false. Only one signature is required in an emergency situation.

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3
Q

1 - In the UK, sterilisation is the most widely used method of contraception

2 - Reversal of female sterilisation is readily available on the NHS

3 - Vasectomy has a lower failure rate than female sterilisation

4 - There is a significantly increased risk of testicular cancer following vasectomy

5 - When counselling a man regarding vasectomy, which of the following is important to stress

A

1 - The answer is false. Sterilisation is the most widely used form of contraception worldwide, but not in the UK. Only 10% of women 16-49 years old are sterilised in the UK.

2 - The answer is false. It is not available in most SHAs.

3 - The answer is true.

4 - The answer is false. There is no evidence of this.

5- Contraception should be used for a further 3 months with a negative semenalysis at the end of that time

  • Vasectomy is reversible but usually not offered within NHS services and although reanastamosis may be successsful , this does not guarantee patency or fertility.
  • Men should be advised that vasectomy is associated with a 1:2000 failure rate in comparison with 1:200 lifetime failure rate for tubal occlusion (2-3:1000 10-year failure rate for occlusion with Filshie clips) and 1:500 5-year failure rate for hysteroscopic sterilization with microinserts.
  • There is no evidence of an increased testicular cancer risk after vasectomy.
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4
Q

Which of the following statements is the most appropriate concerning long-acting reversible contraception and intrauterine devices (IUDs)

1 - Gynefix is currently the only frameless IUD licensed in the UK

2 - IUDs available in the UK are licensed for a variable time period from 5 to 8 years

3 - The most effective IUDs contain at least 280 mm2 of copper

4 - The risk of ectopic pregnancy increases in women using IUDs

5 - Unbanded devices are the most effective IUD presently available

A

Gynefix is currently the only frameless IUD licensed in the UK

  • Currently available IUDs in the UK are effective for 5 or 10 years.
  • The most effective devices contain more than 380 mm2 of copper, and IUDs with copper bands around the arms are the most effective of all as they contain maximum copper.
  • Gynefix is a device constructed of copper beads threaded onto a filament (rather than onto a plastic frame), which is secured in the fundal myometrium.
  • The overall risk of ectopic pregnancy is reduced with use of an IUD compared with using no contraception; however, if a pregnancy does occur with an intrauterine method in situ, the risk of an ectopic pregnancy occurring is increased and in some studies half of the pregnancies that occurred were ectopic.
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5
Q

1 - Approximately 50% of women in the UK discontinue DMPA within 1 year

2 - Progestogen implants are associated with irregular vaginal bleeding

3 - The failure rate of progestogen implants is higher in women with a BMI >40

4 - The major mechanism of action of depomedroxyprogesterone acetate (DMPA) is to thicken cervical mucus

5 - DMPA does not adversely affect bone density in long-term use and, therefore, is recommended as a first-line contraceptive in young women

A

1 - The answer is true.

2 - The answer is true.

3 - The answer is true.

4 - The answer is false. It is to inhibit ovulation.

5 - The answer is false. See the NICE guideline. (link is external) *

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6
Q

CHOOSE ONE BEST

Concerning progestogen-only pills (POPs), which of the following is true?

1 - Additional contraceptive precautions should be taken during antibiotic treatment

2 - In women undergoing treatment for breast cancer, POPs increase the rate of disease recurrence

3 - They are associated with an increased risk of thromboembolic disease

4 - They are contraindicated in women with insulin-dependent diabetes

5 - They should be discontinued 4 weeks prior to major surgery

A
  • The answer is in women undergoing treatment for breast cancer POPs increase the rate of disease recurrence. All hormonal contraception is contraindicated in women who are undergoing treatment for breast cancer as it is a hormone-dependent malignancy.
  • Women with insulin-dependent diabetes may use the POP safely
  • There is no evidence that POPs increases thromboembolic risk
  • There is no evidence that standard antibiotic treatment reduces its contraceptive efficacy.
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7
Q

When counselling a woman for postcoital contraception (PCC), what should you advise

1 - Intrauterine PCC can be inserted up to Day 19 of a 28-day cycle

2 - Mifepristone can be used for PCC

3 - STI screening results should be available prior to fitting intrauterine PCC

4 - The intrauterine system is licensed for PCC
Ulipristal acetate is as effective as an IUD

A

Intrauterine PCC can be inserted up to Day 19 of a 28-day cycle

  • Only copper IUDs are licensed for fitting for PCC.
  • An IUD can be inserted up to day 19 in a 28-day cycle, before the earliest possible implantation of a blastocyst (day 20).
  • IUDs are more effective up to 120 hours after unprotected intercourse (99%), in comparison with oral levenorgestrel (85% effective up to 72 hours and 64% effective up to 120 hours) and oral ulipristal acetate (85% up to 120 hours).
  • Mifepristone has been used as an effective form of PCC in trials but has never been licensed for this purpose in the UK.
  • An IUD can be fitted in an asymptomatic woman as long as she is willing to return for treatment in the event of a positive STI screen.
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8
Q
Method	Failure rate (% pregnant at first year)
Perfect use	Typical use
No method	85	85
Barrier (male)	2	15
Diaphragm	6	16
Combined oral contraceptive
Progestogen-only contraception	0.3	8
Injection	0.3	3
Implant	0.05	0.05
Intrauterine device	0.6	0.8
Intrauterine system	0.1	0.1
Female sterilisation	0.5	0.5
A

Method Failure rate (% pregnant at first year)
Perfect use Typical use
No method:  85 85
Barrier (male) 2 15
Diaphragm 6 16
COC/POC 0.3 8
Injection 0.3 3
____________________________________
Implant 0.05 0.05
IUD 0.6 0.8
IUS 0.1 0.1
Female sterilisation 0.5 0.5

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9
Q
Method	Failure rate (% pregnant at first year)
Perfect use	Typical use
No method	85	85
Barrier (male)	2	15
Diaphragm	6	16
Combined oral contraceptive
Progestogen-only contraception	0.3	8
Injection	0.3	3
Implant	0.05	0.05
Intrauterine device	0.6	0.8
Intrauterine system	0.1	0.1
Female sterilisation	0.5	0.5
A

Method Failure rate (% pregnant at first year)
Perfect use Typical use
No method:  85 85
Barrier (male) 2 15
Diaphragm 6 16
COC/POC 0.3 8
Injection 0.3 3
Implant 0.05 0.05
Intrauterine device 0.6 0.8
Intrauterine system 0.1 0.1
Female sterilisation 0.5 0.5

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10
Q

Which of the above statements is false? Depo-medroxy progestogen acetate should not be prescribed for women…

  • Immediately sfter second trimestr abortion
  • In whom COC pill is contraindicated
  • In woman with Family HX of VTE
  • In woman with personal HX of VTE
  • under 16 years ae
  • At risk of STI or HIV
  • Infected with HIV/AIDS
  • Breast feeding
  • Takin enzyme inducin drus unless dose interval reducced.
  • 2 weeks late for their injection without additional barrier contraceptipn
  • BMI >35
  • HX of focal mirgraine with aura
  • unstable DM
A

Who are taking liver enzyme-inducing medication, unless the dose interval is reduced
Depo-medroxy progestogen acetate can be prescribed for women who are taking liver enzyme-inducing medication

TRUE ANSWERS ARE:Depo-medroxy progestogen acetate should not be prescribed for women…

  • Immediately after second trimester abortion
  • In whom COC pill is contraindicated
  • In woman with Family HX of VTE
  • In woman with personal HX of VTE
  • under 16 years ae
  • At risk of STI or HIV
  • Infected with HIV/AIDS
  • Breast feeding
  • 2 weeks late for their injection without additional barrier contraceptipn
  • BMI >35
  • HX of focal mirgraine with aura
  • unstable DM
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11
Q

Choose the statement relating to progesterone-only contraception methods that is false

  • Acts by preventin ovulation
  • are not contraindicated for use, by breast feedin
  • Doesnot increase risk of ST acquisistion
  • amenorrhea 20 %
  • Irregular bleeding: 50 %
  • reduced dysmenorrhea
  • effective with >70 kg
  • licensed in UK upto 3 years
  • not associated with delay in return of fertility after removal
  • not associated with reuction in BMD
  • not associated with reuced efficacy in < 20 years
  • not associated with weiht gain
  • recomended for taking liver enzyme inducing drugs
A

The answer is progesterone-only contraception methods are recommended for women taking liver enzyme-inducing drugs – they are not recommended for these women.

TRUE ANSWERS ARE:progesterone-only contraception methods

  • Acts by preventing ovulation
  • are not contraindicated for use, by breast feeding
  • Doesnot increase risk of STI acquisistion
  • amenorrhea 20 %
  • Irregular bleeding: 50 %
  • reduced dysmenorrhea
  • effective with >70 kg
  • licensed in UK upto 3 years
  • not associated with delay in return of fertility after removal
  • not associated with reuction in BMD
  • not associated with reuced efficacy in < 20 years
  • not associated with weiht gain
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12
Q

Choose the statement relating to copper IUDs that is false

  • STI screen should be performedd prior to insertion
  • Antibiotic prophylaxis may be considered where risk of STI is significant
  • are associated with increased dysmenorrhea
  • are not associated with delay in return of fertility followin removal
  • are not contraindicated for use by insulin dependant DM
  • Are not contraindicated for use by nulliparous woman under age of 20 years
  • Are not contraindicated for use by woman who is HIV positive
  • Can be used by woman over the ae of 40 years until they no loner require contraception, even if this duration is beyond the UK markettinng authorization
  • Expuslsion occurs in less than 5 %of woman in 5 years of use.
  • If a woman becomes prenant with the IUD in situ the isk of ectopic prenancy is greater than 10%
  • The risk of ectopic prenancy with IUD fitted is lower than when usin no contraception
  • Those with 380mm2 of copper are most effective.
A
  • The answer that is false is if a woman becomes pregnant with the IUD in situ, the risk of ectopic pregnancy is greater than 10%.

TRUE ANSWERS ARE

  • STI screen should be performedd prior to insertion
  • Antibiotic prophylaxis may be considered where risk of STI is significant
  • are associated with increased dysmenorrhea
  • are not associated with delay in return of fertility following removal
  • not contraindicated for use by insulin dependant DM
  • Are not contraindicated for use by nulliparous woman under age of 20 years
  • not contraindicated for use by woman who is HIV positive
  • Can be used by woman over the ae of 40 years until they no loner require contraception, even if this duration is beyond the UK markettinng authorization
  • Expuslsion occurs in less than 5 %of woman in 5 years of use.
  • The risk of ectopic prenancy with IUD fitted is lower than when using no contraception
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13
Q

Choose the statement relating to the Mirena® IUS that is false

  • 50 % of woman becomes amenorrhoeic within the foirst year of use
  • Act predominantly by preventing implantation and sometimes by inhibitin fertilization
  • an STI screen should be performed prior to insertion
  • Anitbitoic prophylaxis may be considered where risk of STI sinificant
  • Are not contraindicated for use by nuliparous woman under 20 years age
  • expulsion occurs less than 5 % of woman in 5 years use
  • If woman becomes prenant with IUS in situ the risk of ectopic prenancy is about 5 %
  • irreular bleedin during first 6 months is common
  • Is associated with acne in some woman
  • Is not contraidicated for use by HIV positive woman
  • Licensed duartion is 5 years for contraception
  • the risk of ectopic prenancy with IUS fitted is lower than usin no contraception
  • no evidence that IUS causes weiht gain
  • When fitted for woman over 45 years of ae, who are amenorrhoeic, the IUS may be used until they no loner require contraception, even if this is the duration of UK marketing authrorization
A

The following statement is false: 50% of women become amenorrhoeic within the first year of use.

TRUE ANSWERS ARE:the Mirena®

  • Act predominantly by preventing implantation and sometimes by inhibitin fertilization
  • an STI screen should be performed prior to insertion
  • Anitbitoic prophylaxis may be considered where risk of STI sinificant
  • Are not contraindicated for use by nuliparous woman under 20 years age
  • expulsion occurs less than 5 % of woman in 5 years use
  • If woman becomes prenant with IUS in situ the risk of ectopic prenancy is about 5 %
  • irreular bleedin during first 6 months is common
  • Is associated with acne in some woman
  • Is not contraidicated for use by HIV positive woman
  • Licensed duartion is 5 years for contraception
  • the risk of ectopic prenancy with IUS fitted is lower than usin no contraception
  • no evidence that IUS causes weiht gain
  • When fitted for woman over 45 years of ae, who are amenorrhoeic, the IUS may be used until they no loner require contraception, even if this is the duration of UK marketing authrorization
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14
Q

An 18-year-old p1+0 (1-year-old child, normal vaginal delivery) attends her local sexual reproductive health clinic requesting contraception. Her first pregnancy was unplanned and she wants a reliable method of contraception, at the same time planning for a further pregnancy in 12–18 months.

She is in a steady relationship and has been with the same partner for 2 years. Her periods are irregular, heavy and painful, and have got worse over recent months, with a cycle of 5–7/21–38 days. She has also noted increased facial hair, requiring electrolysis. She has previously been diagnosed with PCOS. She has no relevant family history. On examination she looks well:

height: 153 cm
weight: 94 kg
BP: 120/75 mmHg.

Choose the method of contraception that is the most suitable for her

  • Condoms
  • Depo-Provera
  • Dianette
  • Mirena
  • Noriday -POP
A

The answer is levonorgestrel IUS (Mirena®).

The Mirena® provides excellent contraceptive protection, is likely to reduce the heaviness and discomfort associated with periods, and also protects endometrium in patients with PCOS.

The Mirena provides immediately reversible contraception for medium and longer term use, enabling her to space pregnancies but without delay to return of fertility. she is in steady relationship; therefore, risk of STI is low & since she is parous fitting the IUS should be straightforward.

  • Dianette® is contraindicated as BMI >40 (UKMEC Category 4).
  • Noriday is less likely to control the menstrual dysfunction and has a higher failure rate if not taken reliably.
  • Depo-provera® is relatively contraindicated due to concerns regarding bone loss in adolescents and delay in return to fertility in this patient who is considering further pregnancy in 12–18 months.
  • Condoms are less effective for contraception and will not help with her menstrual dysfunction.
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15
Q

Miss Y is a 22-year-old nuliparous young woman who presents at her local sexual reproductive health clinic having had unprotected sexual intercourse on day 16 of a regular 28-day cycle. She is in a new relationship, having had intercourse last night with her 27-year-old boyfriend who she met last week at a party.

She has not had any other episodes of unprotected intercourse this cycle. She suffers from epilepsy and takes carbamazepine 400 mg twice daiy. She is otherwise well with no relevant family history. She looks well and her measurements are as follows:

height: 159 cm
weight: 58 kg
BP: 115/65 mmHg.
Choose the method of contraception that is the most suitable for her

  • Inset cu-IUD as PCC and continue to use IUD as her preferred method of contraception
  • Levonelle 1,5 mg Immediately as PCC, repeated after 12 hours, condoms and commence Cerazette POP at the onset of her next period
  • Levonelle 1,5 mg Immediately as PCC, repeated after 12 hours, condoms and commence Depo-provera to be administered every 12 weeks at the onset of her next period
  • Levonelle 1,5 mg Immediately as PCC, condoms and commence Depo-provera to be administered every 10 weeks at the onset of her next period
  • Levonelle 1,5 mg Immediately as PCC, condoms and commence Microynon 30 COC at the onset of her next period
A

Insert a copper IUD as postcoital contraception and continue to use the IUD as her preferred method of contraception

The answer is insert a copper IUD. A copper IUD is the gold-standard of emergency contraception and should be offered to everyone. It would also make good ongoing contraception for someone taking enzyme-inducing medication (carbamazepine). If the patient refuses an IUD, then the unlicensed option of double-dose levonelle (3 mg) should be offered.

Carbamazepine is an enzyme-inducing anticonvulsant that is likely to reduce the contraceptive efficacy of the Levonelle®, which according to the CEU guidelines should be doubled (FSRH; 2012 (link is external)).

Depo-Provera® is unaffected by such agents, whereas the dose of the combined oral contraceptive pill would have to be increased to 50 microgram daily (FSRH; 2017 (link is external)).

Condoms should be advised to reduce STI risk in women in short-term relationships.

A copper IUD should be offered for postcoital contraception but if chosen, should be covered with antibiotic prophylaxis and STI screen and used with condoms in this situation. It has the advantage of not being affected by the enzyme-inducing drugs and, therefore, in this case is the preferred choice.

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16
Q

Mrs P, a 32-year-old para 4+0, has just delivered a baby boy (SVD) following an unplanned pregnancy, having recently separated from her husband and entered into a new short-term relationship. She is a week postpartum and requesting a reliable form of contraception.

She has a family history of VTE in a first-degree relative and is known to carry a protein S deficiency but has never had a VTE episode herself. She is bottle feeding, her puerperium has been uncomplicated and she is keen to start contraception as soon as possible.

Height: 160 cm
Weight: 65 kg
BP: 135/80.
Choose the method of contraception that is the most suitable for her

  • Advice regarding STI and condom use, and injection of Depo-provera after 6 weeks
  • Advice regarding STI and condom use, follow up appointment to discuss male or female sterilization
  • Commence COC (Micrynon 30) 4 weeks postpartum, advice regarding STs and condom use.
  • Commence POP(Cerazette) immediately, advice reardin STI and condom use
  • Immediate insertion of CU-iud (Tsafe, Cu380A) advice regarding STI and condom use
A

Commence progestogen-only pill (Cerazette®) immediately, advise regarding STI and condom use

The answer is commence progesterone-only pill (Cerazette®) immediately, advice regarding STI and condom use.

She has requested immediate contraception and is clearly concerned at the prospect of a further unplanned pregnancy. The progestogen-only pill can be started immediately without additional risk. STI and condom advice are good practice points. The IUD and IUS should not be inserted prior to 4 weeks postpartum because of the risk of uterine perforation.

WHO recommendation is that Depo-Provera® and implants should not be used before six weeks post-partum because of likely bleeding problems. The combined oral contraceptive is absolutely contraindicated here (WHOMEC Category 4; see reference) because of the increased VTE risk with protein S deficiency, a known thrombogenic mutation.

17
Q

Case study 4 – molar pregnancy and contraceptive choice
A 35-year-old para 1+1 has recently undergone surgical management of miscarriage following a proven molar pregnancy. The hCG levels are being monitored and are still significantly elevated. She is continuing to experience irregular vaginal bleeding following the evacuation of the uterus.

On examination:

height: 156 cm
weight: 58 kg
blood pressure: 110/65 mmHg
She is in a long-term relationshipand is requesting contraception.
Which method of contraception is contraindicated?
- Combined hormonal pill : 30m mc EE+ first generation proesteron
- Depo-Provera
- Mirena
- Subdermal implant
- Desogestrel -POP

A

Levonorgestrel IUS (Mirena®)

The answer is levonorgestreal IUS. UKMEC 2016 considers all methods except intrauterine contraception to be safe after gestational trophoblastic disease. This is a change from previous guidance, which all practitioners should be aware of. The guidance notes that:

“A small study including women using POP or DMPA concluded that current use of hormonal contraception is not associated with the development of gestational trophoblastic neoplasia or delayed time to hCG remission.”

With regard to combined hormonal contraception:

“Following molar pregnancy evacuation, the balance of evidence finds COC use does not increase the risk of gestational trophoblastic neoplasia, and some COC users experience a more rapid regression in hCG levels compared with non-users. Limited evidence suggests that use of COC during chemotherapeutic treatment does not significantly affect the regression or treatment of gestational trophoblastic neoplasia compared with women who use a non-hormonal contraception method or DMPA during chemotherapeutic treatment.”

18
Q

Single best answer question 1
A 26-year-old woman comes to your clinic requesting emergency contraception. She is not currently in a stable relationship. She had unprotected intercourse 4 days ago. She is a para 1+2. Her son is 7 months old and she has had two terminations of pregnancy in the past. She is on day 20 of her cycle and has taken EllaOne® 10 days ago. She has no significant medical or surgical history.
What option of emergency contraception is best suited for her?

Copper IUCD insertion and STI risk assessment

Intrauterine system insertion

Norethisterone tablet

Repeat dose of ellaOne®

Two tablets of Levonelle

A

Copper IUCD insertion and STI risk assessment

EllaOne® is a relatively new emergency contraceptive licensed to be used up to 120 hours of unprotected intercourse. It is comprised of ulipristal acetate 30 mg, which is a selective progesterone receptor modulator. FSRH guidance now suggests it can be used more than once in a cycle but its action as a hormone modulator means that hormonal methods of ongoing contraception should not be started for 5 days after taking ulipristal.

This delay in establishing a contraceptive method may put the user at further risk of conception.

Levonelle® is levonorgesterol 1500 mg, which can be used up to 72 hours of unprotected intercourse for emergency contraception. An intrauterine contraceptive device is the most effective emergency contraception, which can be inserted up to 120 hours of unprotected intercourse. Mirena® and norethisterone are not licensed to use as emergency contraception.

Note: the fact that she may have had more than one sexual partner encourages the ‘copper IUCD insertion and STI risk assessment’ option as a choice so she can have the STI risk assessment.

19
Q

Single best answer question 2
A 15-year-old girl is 10 weeks pregnant and has self-referred requesting termination of pregnancy. 
What is not part of a routine consultation?

Check for Gillick’s competency as she is less than 16 years of age
Check Rhesus status as she may need anti-D
Consider child safeguarding issues by asking about details of partner
Explain risks and side effects of procedure
Inform parents as would need general anaesthesia for procedure

A

Inform parents as would need general anaesthesia for procedure
Informing her parents is not an essential criteria and patient confidentiality should be respected. A young adult should be assessed by Fraser guidelines and it should be imperative that she understands the risks and benefits of the procedure and is able to make an informed choice. The patient, however, should be encouraged to inform her parents.

20
Q

Single best answer question 3
A 35-year-old para3 comes to clinic for contraceptive advice. She was advised to come off the combined pill as she developed migraines with aura while taking it. She is now using the diaphragm but is looking for something more reliable.
With regards to duration of action of long-acting reversible contraception, which one of these statements is not correct?

Depo-Provera® injection is effective for 13 weeks

Mirena coil is effective for 5 years

Multiload copper coil is effective for 5 years

Nexplanon® is effective for 3 years

T-Safe® Cu380A is effective for 10 years

A

Nexplanon® is effective for 3 years

Nexplanon® is effective for 3 years. It is a subcutaneous reversible progesterone contraceptive device. It is a 4-cm-long radiopaque flexible tube inserted in the subcutaneous tissue of the upper arm.

21
Q

A 26-year-old para 1 comes to your clinic requesting contraception. She mentions that her maternal aunt had deep vein thrombosis (DVT) and is on warfarin. She is worried that if she takes hormonal contraception she will also develop DVT.
Which of the following advice regardling DVT is incorrect.

Observational studies have reported that the transdermal patch has a somewhat similar level of VTE risk to combined oral contraceptives containing second-generation progestogens

Combined oral contraceptives containing a third generation progestogen is associated with an increased risk of venous thromboemolism (VTE) when compared with those containing second generation progestogens

The risk of VTE increases with the number of years of usage of a combined hormonal pill

There is little or no data to suggest that there is an increased risk of VTE with oral or injectable progesterone only contraceptives methods

Thrombophillia screen is not recommended routinely before use of combined hormonal contraceptive

A

The risk of VTE increases with the number of years of usage of a combined hormonal pill

The correct answer is that the risk of VTE increases with the number of years of usage of a combined hormonal pill. The risk of VTE is highest in the 4 months following the initiation of CHC or when restarting after a break of at least 1 month. The risk then reduces over the next year and remains stable thereafter. Although the risk is high in the first few months of CHC use and then falls, it remains higher than in non-users. While women with reduced levels of naturally occurring anticoagulants (anti-thrombin III, Protein C or Protein S), factor V Leiden, or prothrombin gene mutations are predisposed to VTE, FSRH guidance does not recommend the need for routine thrombophillia screening prior to use of CHC, as a negative screen may not exclude all types of thrombophilia.

22
Q

A couple have come to your clinic requesting sterilisation. After going through the risks and benefits of the procedures they opt for vasectomy.

Which of the following should not be taken into consideration during vasectomy?

  • 12-week postvasectomy is considered an optimal timing for scheduling first postvasectomy semen analysis
  • Clips are not recommended for occlusion of the vas deferens as it is associated with a higher failure rate
  • If motile sperms are found in a fresh semen sample 3 months postprocedure, the vasectomy is be considered a failure
  • Routine histological examination of the vas deferens is no longer routinely recommended
  • Warming local anaesthetic to body temperature before infiltration reduces pain due to injection
A

INCORRECT : If motile sperms are found in fresh semen sample 3 months post-procedure, the vasectomy is be considered a failure.

CORRECT:
- 12 week post-vasectomy is considered an optimal timing for scheduling post-vasectomy semen analysis (PVSA).

  • Postal semen samples can be used for PVSA; however, such samples will not be suitable for assessment of sperm motility.
  • In a small proportion of men non-motile sperms will persist following vasectomy. In such cases special clearance can be given to cease using additional contraception when less than 100 000 non-motile sperms/ml are observed in a fresh semen sample post-vasectomy.
  • If motile sperms are observed 7 months post-vasectomy the procedure should be considered a failure.
  • Clips are not recommended for occlusion of the vas deferens as it is associated with a higher failure rate
  • Routine histological examination of the vas deferens is no longer routinely recommended
  • Warming local anaesthetic to body temperature before infiltration reduces pain due to injection
23
Q

A 27-year-old nulliparous woman comes to the outpatient clinic requesting Depo-Provera® injection. She wants to know about the non-contraceptive benefits and risks with injectable progesterones.

Which of the following is incorrect?

  • Anaemic women may benefit from using injectable progestogens
  • Depot medroxy progesterone acetate is associated with increase in bodyweight
  • Injectable contraceptives have been associated with an increased risk of developing VTE with previous HX of VTE after immobilisation
  • It can reduce pain due to endometriosis
  • Women with sickle cell disease may notice a decrease in pain during sickle cell crisis
A

INCORRECT : Injectable contraceptives have been associated with an increased risk of developing venous thromboembolism in women with a previous history of venous thromboembolism after immobilisation

CORRECT:
- UKMEC indicates that HX of VTE or thrombogenic mutations are conditions where advantages of using prostogen injectables outweigh risks (UKMEC2) and are therefore potential option for women with these conditions.

  • SLE are at increased risk of a number of cardiovascular conditions like ischaemic heart disease, stroke and VTE. It is for this reason that greater CAUTION advised in SLE or APLAS than HX of VTE due to other cause.
  • Anaemic women may benefit from using injectable progestogens
  • Depot medroxy progesterone acetate is associated with increase in bodyweight
  • It can reduce pain due to endometriosis
  • Women with sickle cell disease may notice a decrease in pain during sickle cell crisis
24
Q

You are a ST5 and are currently in a minimal access surgery placement. Your consultant is training you in performing hysteroscopic sterilisation on a 38-year-old woman. She has had three previous normal vaginal deliveries and a history of Chlamydia trachomatis infection at age 19; otherwise no other history of note. At the end of the procedure you are asked to arrange a follow-up ultrasound scan in 3 months’ time in order to confirm occlusion of the fallopian tubes.

Where in the fallopian tubes would the micro-inserts be placed?

Ampullar

Infundibulum

Intraluminal

Intramyometrial

Isthmus

A

Intramyometrial

The correct answer is intramyometrial. Access to the fallopian tubes by hysteroscopy should be aimed at the interstitial compartment (intramyometrial).

25
Q

You are going to prescribe combined transdermal patches for a 15 year old girl with cerebral palsy as she is unable to cope with her periods. For the combined transdermal patches to achieve the same effect as continuous oral contraceptive pill, for how long the patches should be applied serially for?

3 weeks followed by 7-day withdrawal period

4 weeks followed by 7-day withdrawal period

5 weeks followed by 7-day withdrawal period

7 weeks followed by 7-day withdrawal period

9 weeks followed by 7-day withdrawal period

A

9 weeks followed by 7-day withdrawal period

The patches are changed weekly, however, the same effect as continuous oral contraceptive pill, can be achieved by applying patches serially for 9 weeks followed by a 7-day withdrawal period, or used continuously until breakthrough bleeding. For girls with low body weight or those on enzyme inhibiting anti-epileptic drugs, the patches can be divided to reduce the dose and tailored to the need of the patient.