Anti Arryhthmics Flashcards
1
Q
Adverse effects of group 1a
A
Fall in bp
Thrombocytopenia
Diarrhoea
Large doses - cinchonism Tinnitus Deafness Headache Blurring of vision Diplopia Photophobia Confusion Delirium Disorientation Psychosis
2
Q
Moa of 1b
A
Block na channels in activated and inactivated state
Decrease automaticity of ectopic foci by reducing the slope of phase 4 depolarization
3
Q
Adverse effects of lignocaine
A
Headache Drowsiness Blurred vision Confusion Muscle twitching Convulsions
High doses
Hypotension due to myocardial depression
Side effects potentiated in hepatic and renal failure
4
Q
Adverse effects of 1c
A
Both: exacerbate arrhythmia and ccf
Propefenone: Metallic taste Constipation Bradycardia Bronchospasm
Flecainide:
Blurring of vision
5
Q
Ae of b blockers
A
Hypotension Dizziness Bronchospasm in asthmatics Hallucinations Bradycardia Sleep disturbances Sexual dysfunction in males Nightmares
6
Q
Ae of class 3
A
CVS: hypotension
Chf
Exacerbating arrhythmia
Peripheral neuropathy Pulmonary fibrosis Nausea and hepatitis in GIT Photosenstivity and pigmentation of skin Corneal deposits in eye Thyroid: hyper and hypo - monitor tsh t3 t4 during Long term therapy
7
Q
Ae of ca2+ blockers
A
Edema
Sinus bradycardia
Constipation
8
Q
Adenosine ae
A
Asystole Bronchospasm Chest psin Dyspnea Flushing Hypotension Headache
