Epithelium Flashcards

1
Q

What are the four classic tissues?

A

Epithelium

Connective Tissue

Muscle

Nerve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Where do you find epithelium?

A
  1. All internal and external skin surfaces
  2. The gut canal from inner lip to anal skin
  3. All glands associated with internal and external surfaces
  4. line all blood vessels
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where did epithelium arise from?

A

From all three germ layers:

ecto, meso and endoderm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is an enterocyte?

A

Epthelia that lines the small intestine and is a absorptive cell.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the purpose of microvilli?

A

To increase the absorptive surface area.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What kind of junctions hold together epithelial cells?

A

Gap junctions

Tight junctions

Adherens

Desmosomes

Hemidesmosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Does epithelia have blood vessels?

A

No epithelia is avascular.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Why are epithelial cells capable of self renewal?

A

Because they contain stem cells in the basal lamina (basement membrane)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the name of epithelium that lines blood vessels?

A

It is called endothelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What kind of cells that are within epithelium that produces mucus?

A

Goblet Cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the five layers of the epidermis?

A

Cher: Stratum Corneum

Likes: Stratum Lucidum

Hot: Stratum Granulosum

Sex: Stratum Spinosum

Bam: Stratum Basale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

In what layer of the epidermis do cells undergo apoptosis?

A

In the stratum granulosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

In what layer of the epidermis do the stem cells live?

A

In the stratum basale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Through what kind of junctions in the epithelia does intercellular communications occur?

A

Gap junctions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What junction connects intermediate filaments from one cell to the intermediate filaments of another?

A

Desmosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What junction connects the actin filaments from one epithelial cell to the actin filaments in another cell?

A

Adherens

17
Q

What kind of junctions anchor epithelial cells to the basal membrane?

A

Hemidesmosomes

18
Q

What are the three kinds of cytoskeleton in epithelium?

A

Microtubules

Actin Filaments

Intermediate Filaments

19
Q

What kind of epithelial cytoskeleton is not part of cell junctions?

A

Microtubules

20
Q

A cell without good intermediate filaments will?

A

Be weak and rupture when stretched.

***Remember that desmosomes and hemidesmosomes attach intermediate filaments in adjacent epthelial cells.

21
Q

What disease is the result of failed desmoglein or mutations in cytokeratins?

A

Pemphigus (blistering disease)

22
Q

What is the secretory pathway?

A

rER >> Golgi >> Vesicles >> Plasma Membrane

This occurs from the basal to apical layer.

23
Q

What is the difference between merocine, apocrine and holocrine secretion?

A

Merocine: secretory vesicle fusion with plasma membrane.

Apocrine: secretion of vesicle with lipid droplet

Holocrine: Secretion that involves plasma membrane rupture

24
Q

What are the three places we find stem cells in the skin?

A

Epidermal SC in stratum basale

Sebocyte SC in the sebaceous gland

Bulge stem cells in the hair follicle