Bleeding & Hypercoagulable Disorders

Question 1

T/F: congenital bleeding disorders have a lot of variance in penetrance presentation thus affecting the severity of the disorder

Answer 1

true

Question 2

what happens after a vessel is injured?

Answer 2

1. vessel spasm (constricts)
2. platelets adhere to injury site and aggregate to form plug
3. formation of insoluble fibrin strands and coagulation

Question 3

how soon after injury does the vessel spasm and platelets adhere to injury site and aggregate to form plug?

Answer 3

immediate

Question 4

how soon after a platelet plug is formed does the formation of insoluble fibrin strands and coagulation occur?

Answer 4

several hours or longer

Question 5

what will the platelet count tell you?

Answer 5

will only tell you how many platelets that pt has

Question 6

what happens if pt’s platelet count is <50,000?

Answer 6

pt will bleed excessively with minor trauma

Question 7

what happens if pt’s platelet count is <20,000?

Answer 7

pt will have spontaneous bleeding

Question 8

what is the best single screening test for coagulation disorders?

Answer 8

partial thromboplastin time (PTT)

Question 9

what does PTT test?

Answer 9

intrinsic and common pathways