Jaundice

Question 1

Jaundice becomes evident in a newborn when the TSB reaches

Answer 1

5mg/dL or 86micromol/L

Question 2

Bilirubin is the end product of ___ degradation

Answer 2

HEME; which is produced by the breakdown of hemoglobin

Question 3

The conversion of heme to bilirubin occurs mainly in the ___ system of these organs:

Answer 3

reticuloendothelial system of the spleen, liver, and bone marrow

Question 4

Unconjugated bilirubin is tightly bound to ___ during transport to liver

Answer 4

albumin

Question 5

Increased production of bilirubin can result from what four ddx’s?

Answer 5

Physiologic jaundice
Hemolysis (ABO or Rh incompatibility)
Polycythemia
Cephalohematoma