C&P: Physiological Effects of IV Induction Agents Flashcards
1
Q
Blood Pressure
A
Thiopental: reduced Methohexital: reduced Propofol: reduced++ Ketamine: increased Etomidate: no change
2
Q
Cardiac Output
A
Thiopental: reduced Methohexital: reduced Propofol: reduced++ Ketamine: increased Etomidate: no change
3
Q
Heart Rate
A
Thiopental: increased Methohexital: increased Propofol: reduced Ketamine: increased Etomidate: no change
4
Q
Systemic Vascular Resistance
A
Thiopental: Either (wild card) Methohexital: Either (wild card) Propofol: reduced++ Ketamine: no change Etomidate: no change
5
Q
Respiratory Rate
A
Thiopental: reduced Methohexital: reduced Propofol: reduced Ketamine: increased Etomidate: reduced
6
Q
Intracranial Pressure
A
Thiopental: reduced Methohexital: reduced Propofol: reduced Ketamine: increased Etomidate: no change
7
Q
Intraocular Pressure
A
Thiopental: reduced Methohexital: reduced Propofol: reduced Ketamine: increased Etomidate: no change
8
Q
Pain on Injection
A
Thiopental: No Methohexital: Yes Propofol: Yes Ketamine: No Etomidate: Yes
9
Q
Nausea/vomiting
A
Thiopental: No Methohexital: No Propofol: No +?protective Ketamine: Yes Etomidate: Yes
10
Q
Misc
A
Thiopental: crystallizes if intra-arterial injection
Methohexital: reduces fit threshold
Propofol: ?toxic in children (metabolic acidosis and bradycardia)
Ketamine: increased salivation and ‘dissociation’
Etomidate: adrenal suppression
