1 Flashcards
1
Q
P450 inducers
A
PC BRAS:
Phenytoin Carbamazepine Barbiturates Rifampicin Alcohol (chronic excess) Sulphonylureas
2
Q
P450 Inhibitors
A
AO DEVICES:
Allopurinol Omeprazole Disulfiram Erythromycin Valproate Isoniazid Ciprofloxacin Ethanol (acute intoxication) Sulphonamides
3
Q
Drugs that must be stopped before surgery
A
I LACK OP:
Insulin Lithium Anticoagulates/antiplatelets COCP/HRT K-sparing diuretics Oral hypoglycaemics Perindopril and other ACE inhibitors
4
Q
When should COCP/HRT be stopped before surgery?
A
4 weeks
5
Q
When should lithium be stopped before surgery?
A
Day before
6
Q
When should k-sparing diuretics and ace-inhibitors be stopped before surgery?
A
Day of surgery
7
Q
Oral hypoglycaemics and insulin during surgery
A
Patients are nil by mouth, therefore Metformin should be stopped otherwise it would cause lactic acidosis, other oral hypoglycaemics/insulin would cause hypoglycaemia. Sliding scale should be started instead, with hourly blood glucose adjusting dose of insulin = much tighter control
8
Q
Maximum daily dose of paracetamol
A
4g
