Oxytocin + Diabetes Insipidus - Chen

Question 1

3 Ps of Oxytocin

Answer 1

Powers - contraction factors
Passenger - baby position
Passage - stuck

Question 2

When is oxytocin initiated

Answer 2

during stages 2 and 3 of pregnancy

Question 3

Indications for oxytocin

Answer 3

maternal medication conditions
fetal compromise
fetal demise

Question 4

CIs to oxytocin administration

Answer 4

previous uterus incision or rupture
placenta previa
sideways fetus

Question 5

Low dosing of oxytocin

Answer 5

low: 1-2 milliunits/min

Question 6

High dosing of oxytocin

Answer 6

4-6 milliunits/min

Question 7

Max dose of oxytocin

Answer 7

40 milliunits/min

Question 8

Adverse effects of oxytocin

Answer 8

tachysystole

hyponatremia

Question 9

When would higher units be needed

Answer 9

postpartum hemorrhage

medical termination

Question 10

Presentation of Diabetes Insipidus

Answer 10

polyuria
polydipsia
dehydration

Question 11

Mechanism of diabetes insipidus

Answer 11

adh is release > less water is excreted > higher thirst

Question 12

Central diabetes insipidus

Answer 12

deficiency of vasopressin

usually due to hypothalamus damage

Question 13

nephrogenic diabetes insipidus

Answer 13

renal resistance to vasopressin
can be drug induced
Lithium

Question 14

Primary polydipsia

Answer 14

excessive fluid intake leads to vasopressin suppression

no pharmacologic treatment

Question 15

changes in osmolarity in diabetes insipidus

Answer 15

Higher in plasma (>300mOsm)

Decreased in urine (<200mOsm) > lower specific gravity

Question 16

Low solute diet

Answer 16

non-pharm treatment

low sodium and protein

Question 17

Treatment for central diabetes insipidus

Answer 17

chlorpropamide
carbamazepine
thiazides
indomethacin
desmopressin - preferred

Question 18

Treatment for nephrogenic diabetes insipidus

Answer 18

withdrawal drug
salt restriction + thiazide
amiloride
indomethacin