Liver disease - pathology

Question 1

haemolytic anaemia

Answer 1

breakdown of blood
splenomegaly
jaundice
cirrhosis due to too little liver to process it

Question 2

general mechanism of cirrhosis

Answer 2

damage
inflammation 
some regeneration
some healing by fibrosis
fibrosed tissues can become cirrhosed

Question 3

cause of cirrhosis

Answer 3

hepatitis viruses - direct damage or encourage body to produce immune response which damages liver cells

alcohol consumption

Question 4

consequences of cirrhosis

Answer 4

Liver failure

Nodules of cell form within veins - blood less well circulating

Anastomoses of portal vessels leading to portal hypertension –> varices through digestive tract

Ascites due to low albumin production and increased BP –> oedema

hepatocellular carcinoma in extreme cases

Question 5

blockages to flow of bile out of the liver

Answer 5

gallstones
can escape all bladder and enter common bile duct
block flow of bile into duodenum