Immunosuppressive drugs Flashcards

1
Q

Which drug suppressed B and T lymphocytes by specifically inhibiting the de novo synthesis of guanine?

A

Mycophenolate mofetil

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2
Q

Which drug suppresses B and T lymphocytes by inhibiting the de novo synthesis of adenosine and guanine by acting as a prodrug of 6-MP?

A

Azathioprine

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3
Q

Which drugs block signal transduction activating T cells by acting as calcineurin inhibitors?

A

Cyclosporine (CSA) and tacrolimus (FK-506)

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