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Y3 Neurology > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

general mechanism of NSAID

A

cyclooxgenase inhibitors; decrease prostaglandin formation

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2
Q

common side effects of NSAIDs

A

GI irritation/bleeding
renal
CVD (in COX2)

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3
Q

what medication is being described “antipyretic alline derivative”?

A

paracetamol

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4
Q

is paracetamol anti-inflammatory

A

no

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5
Q

main side effect of paracetamol

A

liver

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6
Q

are opioids more effective in chronic pain or nociceptive pain?

A

nociceptive pain

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7
Q

side effects of opioids

A 
N+V
constipation
dizzy/vertigo
somnolence
dry skin
pruritus
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8
Q

give some examples of TCAs

A

amitriptyline

imipramine

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9
Q

give some examples of uses of TCAs

A

neuropathic pain
tension HA
CRPS

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10
Q

general mechanism of TCAs

A

inhibit NA/ serotonin 5-HT uptake

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11
Q

main side effects of TCAs

A

constipation, dry mouth, somnolence, HR, insomnia, >appetite

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12
Q

are anticonvulsants used for nociceptive or neuropathic pain?

A

neuropathic pain

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13
Q

what channel does gabapentin act at

A

voltage dependent Ca channel

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14
Q

give examples of anticonvulsants used for neuropathic pain

A

carbamazepine
gabapentin
pregablin

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15
Q

side effects of anticonvulsants used for neuropathic pain

A

sedation, dizzy, ataxia, peripheral edema, N

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16
Q

anticonvulsants used for neuropathic pain can cause weight gain or loss?

A

gain

17
Q

anticonvulsants used for neuropathic pain can cause peripheral or pulmonary edema?

A

peripheral edema

18
Q

are SSRIs or SNRIs more effective for managing neuropathic chronic pain

A

SNRIs

19
Q

do SSRIs or SNRIs increase or decrease descending inhibition

A

increase descending inhibition

Y3 Neurology (23 decks)

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