drugs Flashcards
1
Q
doxazosin
A
- reversible alpha blocker (mainly a1 subtypes)
- vasodilator
2
Q
labetalol
A
- alpha and beta blocker (blocks all adrenergic receptors)
- used for hypertension in pregnancy
3
Q
carvedilol
A
- congestive HF
- blocks all adrenergic receptors
- also antioxidant properties
4
Q
nifedipine
A
- Ca2+ channel blocker
- acts on resistant vessels
- decreases BP by vasodilation
- used for hypertension and vasospasm
5
Q
verapamil
A
- calcium channel blocker
- acts on conducting tissues
- slows HR = used in rate control
- negative inotrope
- blocks GI channels (constipation)
6
Q
diltiazem
A
- Ca channel blocker
- angina, hypertension, rate control (AF)
- can be used w/ beta blocker
7
Q
metoprolol or atenolol
A
- beta blocker
- decrease HR and cardiac work
- given in angina
8
Q
cilazapril
A
- ACE inhibitor
- used w/ hypertension and CHF
- vasodilation, decrease BV, decrease sympathetic, and decrease cardiac & vascular hypertrophy
9
Q
losartan
A
- angiotensin 2 antagonist
type 1 receptors
10
Q
norepinephrine
A
- first choice vasopressor
- potent a1 agonist = vasoconstriction
- increased peripheral resistance & increased BP
11
Q
digoxin
A
- 3rd line tx for AF (b blocker 1st, diltiazem 2nd)
- used in acute HF patients w/ AF
- decrease HR, increase inotrope
12
Q
dobutamine
A
- B1 agonist
- increase HR & increase contractility
- mostly in heart
13
Q
flusemide
A
- loop diuretic
- inhibits Na/K/Cl co-transporter in ascending loop
- often used w/ ACEi (little anti-hypertensive effect alone)
14
Q
spirolactone
A
- K-sparing diuretic
- antagonist of aldosterone
- inhibit Na/K exchange in CD giving natriuresis
15
Q
bendrofluazide
A
- thiazide diuretic
- inhibits tubular reabsorption in DCT causing natriuesis
(blocks Na/Cl channel in DCT) - effects resistance vessels - opens k channel & hyperpolarises = vasodialtion
- activate RAAS therefore, given w/ ACEi
