Tutorial 3 thyroid disorders

Question 1

How can you differentiate b/w thyrotoxicosis and cancer with hunger

Answer 1

Thyrotoxicosis your appetite goes up, with cancer it goes down

Question 2

Neurological symptoms with hyperthyroidism

Answer 2

Insomnia and irritability

Question 3

What is the name of the antibody which stimulates the receptor in Grave’s

Answer 3

TSH receptor antibody (TRAB)

Question 4

Investigations with grave’s?

Answer 4

TSH and t3/4 (TSH will be low and t3/4 high)
Radioiodine- TSH is required to take it up (but the TSH receptor antibody will do the trick)
TSH receptor antibody test (TRAB)

Question 5

Why isn’t the radioiodine taken up in thyroiditis

Answer 5

Because t3/4 is being released because of an inflammatory condition not because of TSH, so the radioiodine is not taken up

Question 6

Eye signs in hyperthyroid

Answer 6

Periorbital oedema, conjunctival swelling (chemosis), conjunctival injection, exopthalmos, diplopia

Question 7

Treatment in hyperthyroidism

Answer 7

Drugs (carbimazole, PTU)
Radioiodine
Surgery

Question 8

Diagnosis in case 2

Answer 8

Hypothyroidism

Question 9

Investigations for hypothyroidism

Answer 9

TSH (will be high) and T3/4 low