Module 8.12 - Pharyngitis Flashcards

1
Q

What is pharyngitis?

A

An inflammation of the pharynx that is usually associated with tonsillitis; can be acute or chronic.

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2
Q

What causes pharyngitis?

A

A. Viral- most common

  1. Influenza A and B
  2. Adenovirus
  3. Enterovirus

B. Bacterial- (less common)

  1. Group A beta-hemolytic streptococcus (GABHS) NOTE* Complications from GABHS pharyngitis, although rare, include rheumatic heart disease and glomerulonephritis.
  2. Haemophilus influenzea
  3. Neisseria gonorrhoeae
  4. Mycoplasma

C. Fungal – Candida albicans- commonly seen in immunocompromised patients

D. Pharyngitis may be associated with the following:

  1. Esophageal reflux (GERD)
  2. Allergic rhinitis (non-infectious)
  3. Sinusitis
  4. Carcinoma
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3
Q

What are the subjective/physical exam findings associated with pharyngitis?

A

A. Sore or painful throat

B. Dysphagia

C. Fever/chills

D. Malaise/myalgia

Viral:

  1. Edema of lymphoid tissue in the posterior oropharyngeal wall- elevated oval islands.
  2. Pale, boggy mucosae of the posterior pharynx, palatial petechiae
  3. Painful ulcers/blistering in oral cavity/pharynx
  4. Posterior cervical lymphadenopathy

Streptococcal (GABHS) – Centor criteria (fever, tonsillar exudate, tender anterior cervical LAD, but no cough)

  1. Bright red, edematous pharyngeal mucosa
  2. White or yellow exudate

3. Fever greater than 101 degrees F

  1. Anterior cervical lymphadenopathy

Candidal:

  • Shiny, white and raised patches located on the following: posterior pharynx, tongue and buccal mucosa; patches may have erythematous rims (red base).
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4
Q

What lab/diagnostic tests are used to diagnosed pharyngitis?

A

A. Rapid strep antigen screen

B. Throat cultures, CBC with differential (if rapid strep is negative)

C. Mono spot for suspicion of mononucleosis

D. If indicated, culture for chlamydia and/or gonorrhea.

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5
Q

How do you manage a patient with bacterial pharyngitis?

A

A. Pain relief:

  1. Lozenges, OTC prn
  2. Throat sprays, OTC prn
  3. Warm salt water gargle
  4. Systemic analgesics: acetaminophen and NSAIDS
  5. Glucocorticoids are not recommended.

B. Antimicrobial therapy based on GABHS only

  1. Benzathine penicillin (Bicillin L-A) 1.2 million units IM single dose, or penicillin V (Pen-Vee K) 500mg po bid x 10 days.
  2. Cephalexin 500m po bid x 10 days
  3. Cefadroxil, 100mg po daily x 10 days

4. Clindamycin 300mg po tid x 10 days

5. Azithromycin 500mg po daily x 5 days

6. Clarithromycin 250mg po bid x 10 days

  1. Consider antiulcer agents for gastric reflux, such as Omeprazole (Prilosec) 20mg po daily or Lansoprazole (Prevacid) 15-30 mg po daily
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6
Q

How do you manage a patient with candidal pharyngitis?

A

A. Pain relief

  1. Lozenges, OTC prn
  2. Throat sprays, OTC prn
  3. Warm salt water gargle
  4. Systemic analgesics: acetaminophen and NSAIDS
  5. Glucocorticoids are not recommended.

B. For Candida

  1. Nystatin (Mycostatin) 100,000u/mL, take 4-6 mL swish and swallow qid (for mild disease only), or
  2. Fluconazole (Diflucan) 200mg po initially, and then 100mg daily x 14 days (at least)
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7
Q

How do you diagnose a patient with GABHS pharyngitis?

A

A clinical decision rule exists to guide the diagnosis of GABHS:

  • Temperature above 100.9 degrees F = 1 point
  • Recent exposure to a person with GABHS = 1 point
  • Exudates on pharynx or tonsils = 1 point
  • Enlarged or tender lymph nodes = 1 point
  • Cough = -1 point

Patients with two or more points are presumed to have GABHS and should be treated without culture. Patients with one or zero points should have rapid strep test.

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