Peri-op Care: Common Drugs Flashcards

1
Q

Name 3 types of drug that can be used to relieve constipation. What is their MOA?

A
  1. FYBOGEL: high fibre bulk producer which activates stretch receptors in the bowel and triggers peristalsis, and retains water to soften stool
  2. LACTULOSE: osmotic laxative that acts by retaining fluid in the bowel, causing mild osmotic diarrhoea.
  3. SENNA: stimulates peristalsis
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2
Q

What are the side effects of senna? Why should it not be used long term?

A

Side effects:

  • GI discomfort
  • diarrhoea
  • fluid and electrolyte imbalance
  • haematuria
  • albuminuria
  • urine discolouration
  • skin reactions

Should not be used long term as:
- can cause hypokalaemia

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3
Q

What are the side effects of lactulose? Why should it not be used long term?

A

Side effects:

  • abdominal pain
  • flatulence
  • nausea and vomiting
  • electrolyte imbalances (uncommon)

Should not be used long term as:

  • can cause dehydration
  • can cause tolerance
  • doesn’t address underlying issue
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