antimicrobial chemotherapy Flashcards
what is bactericidal
kills bacteria
bacteriostatic
inhibits growth
sensitive
organism is inhibited or killed by antimicrobial
resistant
organism is NOT killed or inhibited by antimicrobial
MBC – MIC
minimum bactericidal/inhibitory concentration
the 3 mechanisms of antibiotics
inhibition of
cell wall synthesis
nucleic acid synthesis
protein synthesis
what do beta lactms do
inhibit PBPs
stop the building of peptidoglycans
what do penicillin inhibit
gram positive
how do cephalosporins
inhibit cell wall synthesis
what are glycolpeptides
act only on gram posotve
given parentally
different ways of drug administration
topical - added to surface
systemic - taken internally
parental - IV or IM (intra muscular)
what do aminoglycosides do
used in treatment of serious gram negative
inhibit protein synthesis
macrolides
stop amino acids bonding
inhibiton of protein synthesis
gram positive infections
example of aminoglycosides
gentamicin
tetracyclines
inhibition of protein synthesis
