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Microbiology 7 > Genus Coxiella > Flashcards

Genus Coxiella Flashcards

1
Q

Classification

A

Family: Coxiellaceae

Genus: coxiella

Species: C.burnetii

Reservoir: domestic livestock

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2
Q

Morphology

A

Gram negative rods
Pleomorphic

Resembles Rickettsia morphologically

Transmission : aerosol

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3
Q

Growth characteristics

A

Aerobic

Obligate intracellular parasite

Highly resistant to heat, drying and some disinfectants

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4
Q

Virulence factors

A
  • no toxins or virulence factors known
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5
Q

Disease

A

Q fever:

  • headache
  • pneumonia
  • fever —> differentiate from Brucella (undulating fever)
  • hepatitis

FEPHH

Complications (in immunocompromised or previously damaged valves) —> endocarditis

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6
Q

Microbiological diagnosis

A
  • via serologic tests usually
  • Weil-felix test negative
  • stain and culture rarely done
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7
Q

Treatment and prevention

A
  • tetracycline —> normally not given due to self-limiting recovery

Prevention
- killed vaccine for persons in high-risk occupations

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Microbiology 7 (18 decks)

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