muscle tissue - structure and function Flashcards

1
Q

skeletal muscle

A

striated, myoglobin present, voluntary control and direct nerve-muscle communication

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2
Q

cardiac muscle

A

striated, myoglobin present, involuntary control, indirect nerve-muscle communication

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3
Q

smooth muscle

A

non-striated, myoglobin absent, involuntary control, no direct nerve-muscle communication

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4
Q

what is myoglobin

A

protein very structurally similar to haemoglobin providing oxygen to working muscle. Haemoglobin will give up oxygen to myoglobin when pH is v low. when muscle is damaged it will cause myoglobin to be relased

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5
Q

components of a muscle cell

A
sarcolemma - membrane 
sarcoplasm - cytoplasm 
sarcosome - mitochondrion 
sarcomere - contraction unit 
sarcoplasmic reticulum - ER of muscle cell
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6
Q

structure of skeletal muscle and its function

A

epimysium - outer layer around cluster of fascicles
perimysium - layer around fascicle
endomysium - layer around muscle fibre within fascicle

The skeletal muscle is joined to tendons which connect it to bone at the point of origin(part that doesn’t move) and insertion(does move during contraction). if these cross a joint it moves and the direction of this movement is dependant on the direction of the muscle fibres

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7
Q

special feature of muscle fibres on tongue

A

muscle tissues is orientated in many different directions allowing for the mobility of the tongue

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8
Q

thin fibres = and thick fibre =

A

thin = less blood and thick = more blood. this is shown by dark red gelatine being injected into an arterial supply

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9
Q

DRAW structure of myofibril

A

z line, I bad ,h zone and a band, I band and z disc

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10
Q

where are fast and slow twitch fibres found

A

long distance = mainly slow twitch fibres
middle distance = mixture of slow and fast
short distance = mainly fast twitch
at-least one of each in each fascicle

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11
Q

features of slow twitch

A
type 1 fibre
rich blood supply 
aerobic
high myoglobin 
many mitochondria 
many cytochromes
red in colour 
fatigue resistant
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12
Q

features of fast twitch

A
type 2 A or B fibre 
poor blood supply 
anaerobic 
low myoglobin 
few mitochondria 
few cytochromes 
white colour 
rapidly fatigued
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13
Q

what is a cytochromes

A

any of a number of compounds consisting of haem bonded to a protein. Cytochromes function as electron transfer agents in many metabolic pathways, especially cellular respiration.

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14
Q

structure of cardiac muscle

A

striations, centrally portioned nuclei and intercalated discs. also has branching

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15
Q

cardiac vs skeletal

A

both striated and have similar contraction mechanisms
BUT
nuclei are central and not peripheral in cardiac, there are no T tubules and only one contractile cell types which is the cardiomyocytes which communicated with other cells via the intercalated disc gap junctions

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16
Q

What is ANP and BNP

A

these are peptides related by the atria and ventricles during heart failure. they reduce arterial pressure by decreasing blood volume and vascular resistance

17
Q

what is hypertrophy

A

enlargement of individual cells

18
Q

what is hyperplasia

A

multiplication of cells

19
Q

atrophy and hypertrophy in heart?

A
H= larger heart than usual 
A= smaller heart than usual
20
Q

what are purkinje fibres

A

conduct an action potentail v rapidly enabling ventricles to contract in synchronisation. They are cells with abundant glycogen, sparse myofibrils and extensive gap junction sites

21
Q

how does the heart conduct

A

look it up

22
Q

features of smooth muscle

A

spindle shaped with single central large nucleus. they are non striated, no sarcomeres or t tubules and capable of being stretched. contraction is slower and more sustained and response to never signals, hormones, drugs or blood gases

23
Q

where is smooth muscle found

A

in vascular structures in gut and respiratory tract

24
Q

what happens when smooth muscle develops a mind of its own

A

high blood pressure, asthma, abnormal gut movement, painful mensuration

25
Q

describe the structure of the smooth muscle of the gut

A

has a longitudinal layer of smooth muscle and a circular layer attached to a mucosal membrane with protrusions and vili to increased the surface area

26
Q

muscle repair in skeletal muscle

A

cannot divide but regenerates by mitotic activity of satellite cells. hyperplasia follows after muscle injury and muscle mass increases

27
Q

muscle repair in cardiac muscle

A

incapable of regeneration. fibroblasts willl invade and lay down scar tissue

28
Q

muscle repair in smooth muscle

A

retain mitotic activity and can form new smooth muscle cells (shown when muscle wall becomes thicker during pregnancy)