Immunology

Question 1

What are the organisms at increased risk for deficiency in:

1. B-cell
2. T-cell
3. Complement
4. Neutrophils

Answer 1

B cell disorders -> antibody deficiency = ENCAPSULATED organisms (usually sinopulmonary infections)

T-cell or combined immunodeficiency disorders = PROTOZOA, FUNGAL, MYCOBACTERIA, ‘INTRACELLULAR’ BACTERIA, VIRUSES (e.g. CMV)

Complement = Bacteria (e.g. Neiserria)

Neutrophils = PYOGENIC bacteria, especially on the skin (e.g. Staph), FUNGAL