Vasoactive Drugs

Question 1

What is the drug class of neosynephrine? (phenylephrine)

Answer 1

Synthetic direct α1 agonist

Question 2

What is the mg/cc for neosynephrine?

Answer 2

10 mg/cc

Question 3

What is the dosing for neosynephrine?

Answer 3

Peds: 1-2 mcg/kg
Adults: 50-100mcg

Question 4

What is the onset, peak, and duration of neosynephrine?

Answer 4

Onset: 30-45 seconds
Peak: 1-2 minutes
Duration: 15-20 minutes

Question 5

What is the drug class of esmolol (brevibloc)?

Answer 5

β1 antagonist

Question 6

What is the mg/cc for esmolol?

Answer 6

10 mg/cc

Question 7

What is the dosing for esmolol?

Answer 7

10 mg or greater for adults

Question 8

What is the onset, peak, and duration of esmolol?

Answer 8

Onset: 2 minutes
Peak: 5 minutes
Duration: 10-15 minutes

Question 9

What is the drug class of ephedrine?

Answer 9

Synthetic indirect and direct α1, β1, β2 agonist

Question 10

What is the mg/cc for ephedrine?

Answer 10

25-50 mg/cc

Question 11

What is the dosing for ephedrine?

Answer 11

5-10 mg incremental doses

Question 12

What is the onset, peak, and duration of ephedrine?

Answer 12

Onset: 1 minute
Peak: 2-5 minutes
Duration: 10-60 minutes

Question 13

What is the Drug class of labetalol (trandate)

Answer 13

α1, β1, β2 antagonist

Question 14

What is the mg/cc for labetalol?

Answer 14

5 mg/cc

Question 15

What is the dosing for labetalol?

Answer 15

0.1-0.5 mg/kg or

5- 10 mg bolus adults

Question 16

What is the onset, peak, and duration of labetalol?

Answer 16

Onset: 1-2 minutes
Peak: 5-10 minutes
Duration: 2-4 hours

Question 17

What is the drug class of hydralazine?

Answer 17

Vascular smooth muscle dilation

Question 18

What is the mg/cc for hydralazine?

Answer 18

20 mg/cc

Question 19

What is the dosing for hydralazine?

Answer 19

2.5-20 mg

Question 20

What is the onset, peak, and duration of hydralazine?

Answer 20

Onset: 10-20 minutes
Peak: 30-60 minutes
Duration: 3-6 hours