Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Cancer Care > Lung > Flashcards

Lung Flashcards

1
Q

What genes are related to non small cell lung cancer?

A

ALK gene overexpression

EGFR gene mutation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the respiratory red flags?

A 
Persistent cough
Haemoptysis 
SoB
Chest pain
Persistent or recurrent chest infections
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What age is the highest peak of lung cancer?

A

80-84

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the lung cancer risk factors?

A 
Smoking including passive
Previous radiotherapy to chest
Occupational exposure: asbestos, acetaldehyde, formaldehyde etc
Family Hx
Germ line mutations
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Where does small cell lung cancer tend to occur?

A

Arises in the large airways therefore more centrally

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What percentage of lung cancers are small cell?

A

20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What paraneoplastic syndromes can occur with small cell lung cancer?

A

Cushings - ACTH

SIADH - ADH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which is the commonest non small cell lung cancer?

A

Squamous cell carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How does SCC lung tend to present?

A

Obstructive lesion of bronchus leading to repeated infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Where in the lungs does adenocarcinomas tend to occur?

A

Peripherally

Or in scar tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How do most lung Ca patients present?

A

Persistent cough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Describe the T staging for lung cancer

A

0 carcinoma in situ
1 <3cm surrounded by lung or visceral pleura
2 >3cm or in main bronchus
3 of any size invading chest wall, diaphragm or parietal pleura
4 of any size invading mediastinum, heart, great vessels, trachea etc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How is local lung cancer treated?

A

Lobectomy or pneumonectomy

Adjuvant chemotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How is locally advanced lung cancer treated?

A

Chemotherapy and radiotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How is metastatic lung cancer treated?

A

Chemotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Cushing’s as a paraneoplastic Syndrome comes from which type of cancer?

A

Small cell lung

17
Q

SIADH as a paraneoplastic syndrome comes from which type of cancer?

A

Small cell lung

And non small cell lung

18
Q

Hypercalcaemia due to raised PTHrp arises from which cancer type?

A

Squamous cell lung

19
Q

How long after asbestos exposure do you get mesothelioma?

A

20-50 years

20
Q

What would a CXR of mesothelioma snow?

A

Thickened, nodular, irregular pleural based mass

21
Q

What investigations are needed for mesothelioma?

A 
Bloods
CXR
CT
Pulmonary function tests 
Biopsy
22
Q

Pulmonary function tests would show what pattern of disease in mesothelioma?

A

Restrictive

23
Q

What is the management of mesothelioma?

A

Surgery (some patients)
Supportive - analgesia, cough suppressant, Abx
RT for mets
Pleural drainage

24
Q

What is the 5 year survival for mesothelioma?

A

5%

25
Q

What is the 5 year survival lung cancer?

A

9%

26
Q

What percentage of lung cancers are due to smoking?

A

80-90%

Cancer Care (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions