Drugs List Flashcards
Drugs used in the management of hypercalcaemia
Fluid (normal saline) and Furosemide (loop diuretic): increased renal Ca2+ excretion
Calcitonin and Alendronic Acid (bisphosphonates): inhibition of Ca2+ release from bone
Drugs used in the management of hypocalcaemia
Generic names: IV calcium gluconate and Vitamin D
MoA: restoration of Ca2+ levels and retention
Drugs used in the management of vitamin D deficiency
Generic names: Vitamin D (cholecalciferol) and Calcitriol (used only in cases of advanced CKD)
MoA: restoration of vitamin D levels
Drugs used in the management of osteoporosis
Generic names: Alendronic acid (bisphosphonates), Raloxifene (SERM), PTH, Denosumab and Vitamin D
MoA: Inhibition of release of Ca2+ from bone by inhibiting osteoclast activity
Anti-proliferative DMARD drugs
Generic names: Methotrexate and Azathioprine
MoA: Reduces lymphocyte proliferation
Immunosuppressive DMARD drugs
Generic names: Sulphasalazine and Penicillamine
MoA: Immunosuppressive mechanism unclear
Biological monoclonal Ab DMARD drugs
Infliximab: Bind and block proinflammatory function of TNFα
Rituximab: Depletion of B cells via CD20
Penicillins (Beta Lactams)
Generic names: Flucloxacillin, Benzylpenicillin and Amoxicillin/Co-Amoxiclav
MoA: Bactericidal causing cell lysis by blocking cell wall synthesis
Carbapenem (Beta Lactams)
Generic name: Meropenem
MoA: Bactericidal causing cell lysis by blocking cell wall synthesis
Cephalosporins
Generic name: Ceftriaxone
MoA: Bactericidal causing cell lysis by blocking cell wall synthesis
Nitroimidazole
Generic name: Metronidazole
MoA: Bacteriostatic effect inhibiting bacterial DNA synthesis
Macrolides
Generic name: Erythromycin
MoA: Bacteriostatic effect inhibiting bacterial protein synthesis
Tetracyclines
Generic name: Tetracycline and Doxycycline
MoA: Bacteriostatic effect inhibiting bacterial protein synthesis
Fluoroquinolones
Generic name: Ciprofloxacin
MoA: Bacteriostatic effect inhibiting bacterial DNA coiling
