Aspergillus lung disease Flashcards

1
Q

Aspergillus lung disease?

A

Lung disease associated with Aspergillus fungal infection. Inhalation of aspergillus spores can produce asperilloma, ABPA or invasive aspergillosis

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2
Q

Aspergillus lung disease Asperilloma?

A

growth of an A. fumigates mycetoma ball in a pre-existing lung cavity.

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3
Q

Aspergillus lung disease ABPA?

A

colonisation of the airways by Aspergillus leads to IgE and IgG-mediated immune responses, occurs in asthmatics.

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4
Q

Aspergillus lung disease invasive aspergillosis?

A

Invasion of Aspergillus into lung tissue and fungal dissemination, occurs in immunosuppressed patients.

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5
Q

Aspergillus lung disease symptoms of aspergilloma?

A

weak haemoptysis

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6
Q

Aspergillus lung disease symptoms of ABPA?

A

difficult to control asthma, recurrant episodes of pneumonia with wheeze

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7
Q

Aspergillus lung disease symptoms of invasive aspergillosis?

A

dyspnoea, rapid deterioration, septic picture.

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8
Q

Aspergillus lung disease signs (4)?

A

tracheal deviation, dullness in affected lung, reduced breath sounds, wheeze cyanosis

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9
Q

Aspergillus lung disease investigations?

A

Aspergilloma: CXR, CT/MRI.

ABPA; same and LFTs

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